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gorskon's profile
David Gorski, MD, PhD
David Gorski, MD, PhD
David Gorski, MD, PhD
Verified account
@gorskon

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David Gorski, MD, PhDVerified account

@gorskon

Surgeon/scientist promoting science in medicine and exposing quackery. Editor of Science-Based Medicine. My opinions do NOT represent those of my employers.

Michigan, USA
sciencebasedmedicine.org
Joined October 2009

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    1. This Tweet is unavailable.
    2. DocMinarchist-Healthcare Is Not a Right‏ @3GHtweets 7 Oct 2020
      Replying to @PaulVCooper1 @angela_bower and

      HCQ is not a vaccine. When Fauci used that terminology he was referring to its prophylactic use which was originally identified in SARS.

      4 replies 0 retweets 2 likes
    3. This Tweet is unavailable.
    4. This Tweet is unavailable.
    5. DocMinarchist-Healthcare Is Not a Right‏ @3GHtweets 7 Oct 2020
      Replying to @PaulVCooper1 @angela_bower and

      Preinfection chloroquine treatment renders Vero E6 cells refractory to SARS-CoV infection https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-2-69 … Antiviral effects here https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(03)00806-5/fulltext#.X1-kUuExGYA.twitter … Meta-analysis of RCTs https://www.medrxiv.org/content/10.1101/2020.09.30.20204693v1 …pic.twitter.com/y3ufAlURrU

      8 replies 2 retweets 1 like
    6. Vicki Allen Crabb‏ @crabb_vicki 7 Oct 2020
      Replying to @3GHtweets @PaulVCooper1 and

      You do realize the risks and benefits of any exposure is determined by epidemiological studies, not in-vitro studies, right?

      3 replies 1 retweet 8 likes
    7. DocMinarchist-Healthcare Is Not a Right‏ @3GHtweets 7 Oct 2020
      Replying to @crabb_vicki @PaulVCooper1 and

      That is incorrect. Epidemiology is useful but the gold standard in therapeutics is either a RCT or meta-analysis, both considered level one evidence, which is why I included this paper:https://www.medrxiv.org/content/10.1101/2020.09.30.20204693v1 …

      5 replies 1 retweet 1 like
    8. Vicki Allen Crabb‏ @crabb_vicki 8 Oct 2020
      Replying to @3GHtweets @PaulVCooper1 and

      You do realize RCTs are epidemiological studies, right? A meta-analysis isn’t a “gold standard”. It’s a study of studies. It provides a pooled effect estimate. It has limitations too.

      0 replies 0 retweets 9 likes
    9. This Tweet is unavailable.
    10. David Gorski, MD, PhD‏Verified account @gorskon 8 Oct 2020
      Replying to @gorskon @crabb_vicki and

      Also, it uses pooled outcomes, which almost always means that the authors couldn't massage the data to come up with a statistically significant result for any really important outcome, such as death or hospitalization. First read, it looks like a crap study to me.

      1 reply 0 retweets 2 likes
      David Gorski, MD, PhD‏Verified account @gorskon 8 Oct 2020
      Replying to @gorskon @crabb_vicki and

      Particularly suspicious, looking at the paper quickly (I'll have to read it in more detail later), I don't see any reports of whether the meta-analysis showed statistically significant results for any of the single outcomes used to make the composite outcome. I'd bet it didn't.

      12:32 PM - 8 Oct 2020
      • 1 Like
      • Queen of the Rÿche
      0 replies 0 retweets 1 like

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