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gorskon's profile
David Gorski, MD, PhD
David Gorski, MD, PhD
David Gorski, MD, PhD
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@gorskon

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David Gorski, MD, PhDVerified account

@gorskon

Surgeon/scientist promoting science in medicine and exposing quackery. Editor of Science-Based Medicine. My opinions do NOT represent those of my employers.

Michigan, USA
sciencebasedmedicine.org
Joined October 2009

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    1. David Gorski, MD, PhD‏Verified account @gorskon 30 Aug 2020

      David Gorski, MD, PhD Retweeted Ashish K. Jha, MD, MPH

      The thing about vaccines is that, because they are preventative measures given to people without disease, it’s not really possible to know if benefits > risks without testing them on large numbers of people; i.e., doing proper phase 3 clinical trials.https://twitter.com/ashishkjha/status/1300080022602969089 …

      David Gorski, MD, PhD added,

      Ashish K. Jha, MD, MPHVerified account @ashishkjha
      .@US_FDA chief @SteveFDA suggesting he could issue EUA for a vaccine if benefit > risk That is totally inappropriate Unlike therapies, which are given to sick people, vaccines are given to healthy people Needs a higher bar Full (expedited) review after completed phase 3 https://twitter.com/AndyBiotech/status/1300048540991922177 …
      8 replies 128 retweets 391 likes
    2. (((Dorit Reiss)))‏Verified account @doritmi 30 Aug 2020
      Replying to @gorskon

      The thing is, an EUA for a Covid-19 vaccine may be the right thing in some circumstances. I think the problem is that at this point, because of their latest actions, we don’t trust the FDA to get the circumstances right.

      1 reply 2 retweets 8 likes
    3. David Gorski, MD, PhD‏Verified account @gorskon 30 Aug 2020
      Replying to @doritmi

      Outside of (possibly) a situation of *incredibly* high community transmission, I can’t imagine a situation where an EUA would be justifiable.

      3 replies 4 retweets 22 likes
    4. (((Dorit Reiss)))‏Verified account @doritmi 30 Aug 2020
      Replying to @gorskon

      We are seeing several communities in that situation. I’m thinking a situation like a nursing home or prison cluster.

      2 replies 0 retweets 0 likes
      David Gorski, MD, PhD‏Verified account @gorskon 30 Aug 2020
      Replying to @doritmi

      The ethics of doing such a thing with vulnerable populations like that is...problematic.

      7:48 AM - 30 Aug 2020
      • 1 Retweet
      • 11 Likes
      • Stewart Lyman Kim Scarpelli Prasad Jallepalli, MD, PhD Edward Nirenberg Crystal English CWebb0412 Matthew Brignall, ND piranha (((Dorit Reiss)))
      2 replies 1 retweet 11 likes
        1. New conversation
        2. (((Dorit Reiss)))‏Verified account @doritmi 30 Aug 2020
          Replying to @gorskon

          Yes. But the ethics of having a preventive at hand and not doing anything are also problematic. Sometimes there isn’t a great answer.

          2 replies 0 retweets 1 like
        3. steven e‏ @stevenpe 30 Aug 2020
          Replying to @doritmi @gorskon

          You don’t have a preventive “at hand” until it’s been shown to be effective and safe. The consequences of getting this wrong for either safety or effect would be unimaginable.

          1 reply 1 retweet 3 likes
        4. Show replies
        1. New conversation
        2. Debunking Denialism‏ @debunkdenialism 30 Aug 2020
          Replying to @gorskon @doritmi

          In places nursing homes or prisons, merely applying social distancing and basic hygiene routines has been shown to be quite effective in limiting disease spread. So it is very unlikely to justify an EUA, since there would already be effective methods available.

          2 replies 1 retweet 0 likes
        3. Matthew Brignall, ND‏ @drbrignall 30 Aug 2020
          Replying to @debunkdenialism @gorskon @doritmi

          That's only sort of true. In my area, we've had double digit fatalities in a number of facilities, even with cohorting, droplet precautions, etc. Also, note that memory care and psych facilities make these steps close to impossible.

          0 replies 0 retweets 0 likes
        4. End of conversation

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