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gorskon's profile
David Gorski, MD, PhD
David Gorski, MD, PhD
David Gorski, MD, PhD
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@gorskon

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David Gorski, MD, PhDVerified account

@gorskon

Surgeon/scientist promoting science in medicine and exposing quackery. Editor of Science-Based Medicine. My opinions do NOT represent those of my employers.

Michigan, USA
sciencebasedmedicine.org
Joined October 2009

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    1. Zoë McLaren, PhD‏ @ZoeMcLaren 2 Aug 2020

      Skipping Phase 3 of clinical trials and rushing out a COVID-19 vaccine is a *terrible* idea. It goes against medical ethics, puts people at greater risk and undermines trust in the vaccine approval system. It causes more problems than it tries to solve. Let me explain. 1/10

      130 replies 4,002 retweets 14,871 likes
      Show this thread
    2. Eric Feigl-Ding‏Verified account @DrEricDing 2 Aug 2020
      Replying to @ZoeMcLaren

      I did NOT advocate for skipping Phase 3. That is absolutely inaccurate. I said in my full thread to expand Phase 3 access to people in epidemic hotspots who wants to volunteer with 50/50% randomization. Do not misquote or misinterpret what I said. Also tag @StevenSalzberg1

      18 replies 23 retweets 212 likes
    3. Steven Salzberg‏ @StevenSalzberg1 2 Aug 2020
      Replying to @DrEricDing @ZoeMcLaren

      I didn't advocate for skipping phase 3 either - not at all. But Twitter doesn't allow for subtlety

      3 replies 0 retweets 27 likes
    4. Paul Falzer‏ @prf5 2 Aug 2020
      Replying to @StevenSalzberg1 @DrEricDing @ZoeMcLaren

      Quoting you: "We don't have to wait months for phase 3 trials of #COVID19 vaccines to finish. We have safe vaccines already, and millions of people (including me) would take them now if permitted. Just do it." If you aren't advocating skipping phase 3, please hone your messaging

      1 reply 0 retweets 20 likes
    5. David Gorski, MD, PhD‏Verified account @gorskon 2 Aug 2020
      Replying to @prf5 @StevenSalzberg1 and

      Yep. As a writer, when people misconstrue what I meant, the first thing I do is to look at what I wrote and ask if it was a failure on my part to communicate well what I meant. Steve sure came across as advocating bypassing phase 3.

      1 reply 0 retweets 11 likes
      David Gorski, MD, PhD‏Verified account @gorskon 2 Aug 2020
      Replying to @gorskon @prf5 and

      It’s bad form for a writer to blame first his readers for misunderstanding him, rather than asking first if he screwed up communicating what he meant.

      7:16 PM - 2 Aug 2020
      • 14 Likes
      • Mel Anderson (((Mark))) DragonPharmD 💙 Scott Johnson+ Sandra Woods, CIPP/C (she/her) 😷🇨🇦 ACNH, ACAB D Mus #Hell'sWaitingForYouDevils KC
      2 replies 0 retweets 14 likes
        1. New conversation
        2. David Gorski, MD, PhD‏Verified account @gorskon 2 Aug 2020
          Replying to @gorskon @prf5 and

          In essence, giving out millions of doses of a vaccine would render the completion of a concurrent phase 3 trial impossible. Why would anyone enroll and risk getting a placebo when they don’t have to? Why wouldn’t everyone conclude that the vaccine must work?

          2 replies 0 retweets 1 like
        3. Paul Falzer‏ @prf5 2 Aug 2020
          Replying to @gorskon @StevenSalzberg1 and

          Paul Falzer Retweeted Zoë McLaren, PhD

          @ZoeMcLaren discussed the folly of bypassing phase 3 in a recent thread. It's worth a look.https://twitter.com/ZoeMcLaren/status/1290003562601185280?s=20 …

          Paul Falzer added,

          Zoë McLaren, PhD @ZoeMcLaren
          Skipping Phase 3 of clinical trials and rushing out a COVID-19 vaccine is a *terrible* idea. It goes against medical ethics, puts people at greater risk and undermines trust in the vaccine approval system. It causes more problems than it tries to solve. Let me explain. 1/10
          Show this thread
          0 replies 0 retweets 0 likes
        4. End of conversation
        1. New conversation
        2. Paul Falzer‏ @prf5 2 Aug 2020
          Replying to @gorskon @StevenSalzberg1 and

          My guess is that @StevenSalzberg1 wrote a hasty tweet and was constrained by 280 characters. He didn't blame readers. However, the tweet was based on his essay published today in Forbes. I don't see any room for doubt about what he is advocating.https://www.forbes.com/sites/stevensalzberg/2020/08/02/start-vaccinating-now/#147f7229cf6e …

          1 reply 0 retweets 1 like
        3. David Gorski, MD, PhD‏Verified account @gorskon 2 Aug 2020
          Replying to @prf5 @StevenSalzberg1 and

          I read it. It’s basically #RightToTry for a #COVID19 vaccine and, as any clinical trialist knows, would basically make completing the necessary Phase 3 trial impossible. The real world practical effect would be to bypass phase 3 trials.

          2 replies 4 retweets 16 likes
        4. Show replies

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