I got it wrong about something. It turns out that @TheLancet #hydroxychloroquine/#COVID19 study was likely fraudulent, thanks to a small, very dodgy company called Surgisphere. Here, I admit my error and try to set things right.https://respectfulinsolence.com/2020/06/05/surgisphere-debacle/ …
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Oh, and one more thing: Those claiming I was trying to avoid the issue were full of
. It takes even me a few hours to write one of my 4,000 word posts. While you thought you were taunting me, I was writing, and smiling.
2 replies 5 retweets 52 likesShow this thread -
Finally, unlike some people who are wrong about something—cough, cough, Very Eminent Rising Star in Oncology—I'm not going to go back and delete my Tweets about this study, even though they now embarrass me. I understand the temptation, but I won't do it.
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One more thing. There are still plenty of observational studies that strongly suggest that
#Hydroxychloroquine probably doesn't work against#COVID19. Even with the Surgisphere/Lancet study gone, that doesn't change. Wait for the RCTs, and don't use the drug outside of an RCT.9 replies 5 retweets 76 likesShow this thread -
Replying to @gorskon
This retraction changes little to nothing in the big picture. Thanks for addressing it so quickly cause I love citing your posts. The deniers, however, will always find something to cling to no matter what.
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Replying to @RyanMarino
That is correct. As I said in my post, before the Surgisphere study, there were already a number of observational studies that failed to find even a hint of a signal of benefit from
#Hydroxychloroquine in#COVID19 patients. Retraction of this study doesn't change that.1 reply 0 retweets 4 likes
Moreover, the plausibility and prior probability for #Hydroxychloroquine to be effective against #COVID19 are both low, given its long history of antiviral activity in vitro that has always failed to translate to antiviral activity in humans in clinical trials.
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