Hmmm. It’s rather interesting to me that something like this can be published without even a consideration of the test used was sensitive enough to test the hypothesis under study.https://twitter.com/GermHunterMD/status/1267577255972106245 …
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Yes, very strange.
Unfortunately it is not uncommon. I deal with Quantitative assays and we get a lot of stakeholders taking BLQ results from us (after promising they know the limitations) then doing statistical comparisons on them!
The next person who tells me that a doubling of cytokine levels from baseline is significant will get a pipette stored inapropriately.
LOD/LOQ. Lab 101? FFS!
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