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gorskon's profile
David Gorski, MD, PhD
David Gorski, MD, PhD
David Gorski, MD, PhD
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@gorskon

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David Gorski, MD, PhDVerified account

@gorskon

Surgeon/scientist promoting science in medicine and exposing quackery. Editor of Science-Based Medicine. My opinions do NOT represent those of my employers.

Michigan, USA
sciencebasedmedicine.org
Joined October 2009

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    David Gorski, MD, PhD‏Verified account @gorskon 29 Apr 2020

    David Gorski, MD, PhD Retweeted Amy G Dala MD

    Agreed. Anyone who describes what sounds like a phase I/II clinical trial as a “game changer” is engaging in marketing more than research.https://twitter.com/AmyGDalaMD/status/1255336392130994176 …

    David Gorski, MD, PhD added,

    Amy G Dala MD @AmyGDalaMD
    Replying to @joe_deasy @MohammadKhanMD @HenningWillers
    As an IRB reviewer, if it's phase 1/2 trial with informed consent it may be reasonable. But PI using phrases like "trial that promises to improve patient outcome" & "game changer" is less reasonable. Would make one very skeptical of their ability to be objective about outcomes...
    4:21 AM - 29 Apr 2020
    • 12 Retweets
    • 65 Likes
    • Andrew S CWebb0412 Chris Helik P Weinberg Lead Engines Santiago Paz Rebecca Larsen Gmary Dan Sontheimer MD
    2 replies 12 retweets 65 likes
      1. New conversation
      2. Amy G Dala MD‏ @AmyGDalaMD 29 Apr 2020
        Replying to @gorskon

        Also makes me *very* uncomfortable with their ability to truly get "informed consent." No one should be making promises with a phase 1 trial. And the consent process should be transparent, objective, noncoercive, & unbiased. Hope the PI is reflecting on these comments & feedback.

        2 replies 1 retweet 15 likes
      3. David Hill‏ @maddog1066 29 Apr 2020
        Replying to @AmyGDalaMD @gorskon

        The logistics of this trial are difficult in the best of settings. Moving critically ill non-intubated COVID patients has risks to patients and staff. There are animal models of COVID19. Prove this works there before even thinking of phase I in humans.

        0 replies 0 retweets 1 like
      4. End of conversation
      1. The Reverse Thinking Man‏ @TheReverseThin1 29 Apr 2020
        Replying to @gorskon

        David, you are not providing data. This is unscientific. Science does not work by saying they are fake. You have to demonstrate they are wrong.

        0 replies 0 retweets 0 likes
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