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gorskon's profile
David Gorski, MD, PhD
David Gorski, MD, PhD
David Gorski, MD, PhD
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@gorskon

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David Gorski, MD, PhDVerified account

@gorskon

Surgeon/scientist promoting science in medicine and exposing quackery. Editor of Science-Based Medicine. My opinions do NOT represent those of my employers.

Michigan, USA
sciencebasedmedicine.org
Joined October 2009

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    1. Nataniel Lester-Coll, MD‏Verified account @DrLesterColl 12 Apr 2020
      Replying to @aribindi @gorskon @NPR

      IRB member here. This is absolutely human subjects research and requires IRB approval.pic.twitter.com/7Izw841Zi0

      2 replies 0 retweets 22 likes
    2. Vamsi Aribindi‏ @aribindi 12 Apr 2020
      Replying to @DrLesterColl @gorskon @NPR

      https://irb.research.chop.edu/quality-improvement-vs-research … Other IRBs would seem to disagree with you. Yes, he would need approval for a retrospective review before he published the data. Most IRBs wouldn't require a prospective one.

      2 replies 0 retweets 3 likes
    3. Nataniel Lester-Coll, MD‏Verified account @DrLesterColl 12 Apr 2020
      Replying to @aribindi @gorskon @NPR

      Thank you for providing a link which very clearly deliniates the difference between QI and research. Giving a drug to human subjects for the purpose of “knowledge-seeking” intended to “answer a question or test a hypothesis" that "may put subjects at risk” is…research, not QI.pic.twitter.com/ohhv7FTs7D

      1 reply 0 retweets 12 likes
    4. Vamsi Aribindi‏ @aribindi 12 Apr 2020
      Replying to @DrLesterColl @gorskon @NPR

      If you read one of the articles posted earlier, Dr. Robin Armstrong states he is doing what he would want done "for his mother or father". Which implies rather strongly he is giving the drug for the purpose of treating his patients, with answering a research question secondary.

      4 replies 0 retweets 1 like
    5. This Tweet is unavailable.
    6. Vamsi Aribindi‏ @aribindi 12 Apr 2020
      Replying to @HawkguyClint @DrLesterColl and

      ? I'm part of a project right now to improve informed consent in pediatric surgical populations. Our plan was to use a new video, wrist band, and other procedures to improve communication of a surgery's details to parents.

      1 reply 0 retweets 0 likes
    7. This Tweet is unavailable.
    8. Vamsi Aribindi‏ @aribindi 12 Apr 2020
      Replying to @HawkguyClint @DrLesterColl and

      "Unapproved" in what way? I give aspirin to patients who have heart attacks and undergo cardiac surgery. That's not approved by the FDA. I don't have a long discussion with patients about it either.

      0 replies 0 retweets 0 likes
    9. This Tweet is unavailable.
    10. Vamsi Aribindi‏ @aribindi 12 Apr 2020
      Replying to @HawkguyClint @DrLesterColl and

      If I wanted to publish a study on it, would I need a retrospective IRB authorization after I did it, or a prospective one? If I started Rx-ing aspirin to all such patients for their clinical benefit, and then "looked back" at how they did, I would need a retrospective IRB.

      1 reply 0 retweets 0 likes
      David Gorski, MD, PhD‏Verified account @gorskon 12 Apr 2020
      Replying to @aribindi @HawkguyClint and

      It's one thing if you do something and then LATER decide you want to publish a retrospective analysis of the outcomes. It's quite another if you do something knowing that you want to publish the results.🙄

      11:42 AM - 12 Apr 2020
      • 5 Likes
      • Tony Photon Clint Barton Skyler Johnson, MD Michael McHale Barbie Siesta
      1 reply 0 retweets 5 likes
        1. New conversation
        2. Vamsi Aribindi‏ @aribindi 12 Apr 2020
          Replying to @gorskon @HawkguyClint and

          But what makes something research or QI isn't whether you want to publish it or not. It's whether you decide there is scientific equipoise between the treatment options or not. If you believe there is, its always research, and if you don't, it's QI.

          1 reply 0 retweets 0 likes
        3. Vamsi Aribindi‏ @aribindi 12 Apr 2020
          Replying to @aribindi @gorskon and

          This guy clearly believes that equipoise does not exist. He believes the evidence supports HCQ administration in his patients. That (erroneous) belief means that he is practicing medicine, not doing n human experiment; and makes data collection QI, not clinical research

          1 reply 0 retweets 0 likes
        4. Show replies

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