This is, of course, BS whataboutism. I’m merely going after the biggest target first.
https://twitter.com/DanLairdMD/status/1247533649089581057 …
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Replying to @gorskon
@DanLairdMD Well there is the fact that Remdesivir has a bit more cred due to previous controlled studies in primates at the very least. It’s a little more concerning that we’re hoarding a drug only studied in vitro & uncontrolled w/ poor pt selection so it’s kind of a big deal.1 reply 0 retweets 4 likes -
Replying to @kellroark @gorskon
EZ 3-Step Plan for folks who believe using malarial drugs experimentally for coronavirus is stupid and dangerous: 1. If you get corona refuse the medicine. 2. If your family gets corona refuse the medicine. 3. Recognize patients have a legal right to choose their own treatment.
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Replying to @DanLairdMD @kellroark
4. Consent to be enrolled on a randomized clinical trial of the drug. #4 is the correct answer, by the way.

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Replying to @gorskon @kellroark
And, no, legally, patients don't need to be enrolled in a randomized clinical trial to use a meds off-label. At least 20 % of medications are prescribed off-label. Some off-label uses of HCQ are the standard of care- pediatric interstitial lung disease, pyphoria cutanea tarda.
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Replying to @DanLairdMD @gorskon
Technically, MCTD, Scleroderma, Sjogren’s etc are also “off label”. But the clinical evidence of use is well studied in such patients. There is a huge difference b/t off label w/ controlled study & off label hoarding w/o controlled study.
2 replies 0 retweets 1 like
Precisely. It’s hard to believe that so many MDs have so little dedication to EBM and even less in the way of critical thinking skills, but there you go.
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