Reasons to not get over excited about hydroxychloroquine: 1. Early promising therapies often disappoint 2. There are known toxicities & dangerous drug interactions 3. People need these meds for evidence-based indications (eg., RA, SLE) Wait for the studies. Don't hoard.
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Then came Raoult's uniquely uninformative case series. Finally, there were two Chinese randomized trials, one negative and one with serious flaws that made it also uninformative. On this evidence base,
#Hydroxychloroquine has become, in essence, standard of care for#COVID19. -
This is a failure of physicians and evidence-based medicine on an epic scale. In our panic due to the virus, we have bypassed the clinical trial process almost completely and adopted an unproven drug with real toxicity as, in essence, standard of care for
#COVID19. - Show replies
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