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gorskon's profile
David Gorski, MD, PhD
David Gorski, MD, PhD
David Gorski, MD, PhD
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@gorskon

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David Gorski, MD, PhDVerified account

@gorskon

Surgeon/scientist promoting science in medicine and exposing quackery. Editor of Science-Based Medicine. My opinions do NOT represent those of my employers.

Michigan, USA
sciencebasedmedicine.org
Joined October 2009

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    1. David Gorski, MD, PhD‏Verified account @gorskon 27 Mar 2020

      The study cited by @khoekstra where hydroxychloroquine and azithromycin were claimed to be able to "cure" #COVID19 had such glaring methodological flaws and downright incompetent analysis that it really showed in essence nothing. 2/https://sciencebasedmedicine.org/are-hydroxychloroquine-and-azithromycin-an-effective-treatment-for-covid-19/ …

      3 replies 22 retweets 62 likes
      Show this thread
    2. David Gorski, MD, PhD‏Verified account @gorskon 27 Mar 2020

      The only currently reported clinical trial of chloroquine to treat #COVID19 was a negative study. 3/ https://www.forbes.com/sites/tarahaelle/2020/03/25/chloroquine-use-for-covid-19-shows-no-benefit-in-first-small-but-limited-controlled-trial/ …

      5 replies 6 retweets 28 likes
      Show this thread
    3. David Gorski, MD, PhD‏Verified account @gorskon 27 Mar 2020

      Granted, it was a small study; so it's possible there's an effect that will show up in the larger studies under way, but, given this result, there is no reason to forego clinical trials and give these drugs off trial now. 4/

      1 reply 2 retweets 22 likes
      Show this thread
    4. David Gorski, MD, PhD‏Verified account @gorskon 27 Mar 2020

      There are also real world consequences to the hype around these drugs. For one thing, they are not benign. The doses used in the existing clinical trials were high. Although rare, these drugs can cause fatal arrhythmias. 5/

      1 reply 2 retweets 28 likes
      Show this thread
    5. David Gorski, MD, PhD‏Verified account @gorskon 27 Mar 2020

      For another thing, the hype has led to hoarding, making it hard for patients who actually benefit from these drugs to get them. These patients suffer if these drugs are diverted before we know if they work. 6/

      1 reply 4 retweets 31 likes
      Show this thread
    6. David Gorski, MD, PhD‏Verified account @gorskon 27 Mar 2020

      Given that background, it was entirely reasonable of the state to crack down on the prescribing of these drugs, particularly outside of hospitals, to prevent or treat #COVID19. 7/

      1 reply 1 retweet 25 likes
      Show this thread
    7. David Gorski, MD, PhD‏Verified account @gorskon 27 Mar 2020

      The narrative that the state is somehow hampering the efforts of doctors in Michigan to treat #COVID19 by restricting the use of these drugs is partisan propaganda, not fact. 8/

      1 reply 2 retweets 32 likes
      Show this thread
    8. David Gorski, MD, PhD‏Verified account @gorskon 27 Mar 2020

      Basically, this @DetNewsOpinion op-ed by @khoekstra is nothing more than a deceptive attack on what was a reasonable order rooted in science and medicine. Quelle surprise, though, given that it's the Detroit News and Hoekstra's with @PacificLegal. 9/9

      2 replies 2 retweets 28 likes
      Show this thread
    9. David Gorski, MD, PhD‏Verified account @gorskon 27 Mar 2020

      Whoa. I've changed my opinion. I used to think that the study cited by Hoekstra was just incompetently designed, carried out, and analyzed. Now I think it was more likely scientific fraud. 9a/9https://forbetterscience.com/2020/03/26/chloroquine-genius-didier-raoult-to-save-the-world-from-covid-19/ …

      9 replies 38 retweets 85 likes
      Show this thread
    10. Jon Ashley‏ @ashleyj722AFKJC 27 Mar 2020
      Replying to @gorskon @schneiderleonid

      He looks like the second coming.

      2 replies 0 retweets 0 likes
      David Gorski, MD, PhD‏Verified account @gorskon 27 Mar 2020
      Replying to @ashleyj722AFKJC @schneiderleonid

      And he now has another study. Of course, it’s not randomized. It’s single arm. To my initial read, it doesn’t really show much of anything about whether hydroxychloroquine and azithromycin work against #COVID19. https://www.mediterranee-infection.com/wp-content/uploads/2020/03/COVID-IHU-2-1.pdf …

      3:32 PM - 27 Mar 2020
      • 2 Retweets
      • 12 Likes
      • Evander ☭🌷🕯 Cristian Riquelme karine labonne Dr Clarisse Audigier-Valette😷🫁 rather be on another planet John Mashey Pouet PDDrKatjaBaerenfaller Muscaria
      3 replies 2 retweets 12 likes
        1. Muscaria‏ @conazole 27 Mar 2020
          Replying to @gorskon @schneiderleonid @ashleyj722AFKJC

          Muscaria Retweeted PDDrKatjaBaerenfaller

          Have you seen this? Another terribly flawed paper:https://twitter.com/jaggakatja/status/1243343083086983168 …

          Muscaria added,

          PDDrKatjaBaerenfaller @jaggakatja
          And futher down the Raoult rabbit hole: https://www.sciencedirect.com/science/article/pii/S0924857920300972 … The claim of this study is that the mortality rate for common coronaviruses is not significantly different to that for SARS-CoV-2 (1/x)
          Show this thread
          0 replies 0 retweets 2 likes
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        1. David M‏ @Swen90210 28 Mar 2020
          Replying to @gorskon @ashleyj722AFKJC @schneiderleonid

          Raoult is just have having fun with people like you who do not understand maths. He just "forgot" to mention in the articles that average covid duration was 20 days in China. Read the articles again.

          0 replies 0 retweets 0 likes
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