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gorskon's profile
David Gorski, MD, PhD
David Gorski, MD, PhD
David Gorski, MD, PhD
Verified account
@gorskon

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David Gorski, MD, PhDVerified account

@gorskon

Surgeon/scientist promoting science in medicine and exposing quackery. Editor of Science-Based Medicine. My opinions do NOT represent those of my employers.

Michigan, USA
sciencebasedmedicine.org
Joined October 2009

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    3. Christina‏ @renissance_1 11 Dec 2019
      Replying to @Sarah_Mojarad

      @gorskon @CaulfieldTim @MarkHoofnagle pinging you all.

      1 reply 1 retweet 2 likes
    4. Mark Hoofnagle‏ @MarkHoofnagle 11 Dec 2019
      Replying to @renissance_1 @Sarah_Mojarad and

      It basically has every single bullshit buzzword from detox to antioxidant. There is no evidence of any such regimen providing benefit in any context. You can’t outsmart your body’s physiology with a vitamin overdose. Prima facie bunkum.

      2 replies 3 retweets 13 likes
    5. Dr Monya De MD MPH‏ @medjournalist 11 Dec 2019
      Replying to @MarkHoofnagle @Sarah_Mojarad and

      antioxidant is not a buzzword-coq10 is a legitimate antioxidant but the real question is does it treat a post MDMA syndrome.

      3 replies 1 retweet 3 likes
    6. Mark Hoofnagle‏ @MarkHoofnagle 11 Dec 2019
      Replying to @medjournalist @Sarah_Mojarad and

      There is *no evidence* of benefits from antioxidants. That is a failed hypothesis and the ultimate dead parrot of woo. If anything they significantly increase mortality, especially supplementation with lipophilic antioxidants.https://jamanetwork.com/journals/jama/article-abstract/205797 …

      5 replies 4 retweets 25 likes
    7. Dr Monya De MD MPH‏ @medjournalist 12 Dec 2019
      Replying to @MarkHoofnagle @Sarah_Mojarad and

      This was likely written and submitted in 2006. So, 14 years old. It is a meta-analysis involving just a few antioxidants. With an an extremely limited endpoint. Mortality. There are millions of patients interested in things like feeling better from their chronic illness or

      3 replies 1 retweet 0 likes
    8. Dr Monya De MD MPH‏ @medjournalist 12 Dec 2019
      Replying to @medjournalist @MarkHoofnagle and

      Being able to discontinue an Rx or having improved body function in an area like sports performance, cognition, sperm count, recovery from injury or shortening the common cold. Antioxidants and other supplements show promise in many of these areas. It is hugely unwise to

      4 replies 1 retweet 0 likes
    9. Dr Monya De MD MPH‏ @medjournalist 12 Dec 2019
      Replying to @medjournalist @MarkHoofnagle and

      discount patient reports , small studies, and animal studies. Funding the huge fancy studies that get into JAMA barely happens as Merck does not care if vitamin E helps your psoriatic arthritis. So bringing whether or not you will die in 30 years or 45 after a lifetime of

      2 replies 1 retweet 0 likes
    10. Mark Hoofnagle‏ @MarkHoofnagle 12 Dec 2019
      Replying to @medjournalist @Sarah_Mojarad and

      So, the real high quality data should be discounted because it's a little bit old, but we should pay attention to the small studies and patient reports because of, what exactly? Privilege? It's also nonsense that there isn't a huge amount of money in vitamins to do this work.

      2 replies 2 retweets 4 likes
      David Gorski, MD, PhD‏Verified account @gorskon 12 Dec 2019
      Replying to @MarkHoofnagle @medjournalist and

      And, interestingly, she doesn’t bother to cite this allegedly copious evidence.🙄

      10:48 AM - 12 Dec 2019
      • 2 Retweets
      • 3 Likes
      • Emily Team Pfizer 💉 Christina (((Dorit Reiss))) Liz "The Mask Goes Over Your Nose AND Mouth" Ditz
      2 replies 2 retweets 3 likes
        1. New conversation
        2. Mark Hoofnagle‏ @MarkHoofnagle 12 Dec 2019
          Replying to @gorskon @medjournalist and

          I stand by it. Advertising anti-oxidant properties is evidence of bunkum, because on the whole the evidence shows they increase mortality vs do nothing. If there's an edge case (vit C treats scurvy!) great fine. But antioxidant !=good or safe and people who use it so go quack.

          1 reply 0 retweets 1 like
        3. Sarah Mojarad  🌿‏ @Sarah_Mojarad 12 Dec 2019
          Replying to @MarkHoofnagle @gorskon and

          Thank you all for chiming in!

          1 reply 0 retweets 1 like
        4. Show replies
        1. New conversation
        2. Dr Monya De MD MPH‏ @medjournalist 12 Dec 2019
          Replying to @gorskon @MarkHoofnagle and

          It's on PubMed, you are smart enough to find. The JAMA is not high quality, two of the three increase-mortality suspects are not something we would prescribe to a person with normal nutrition, so studying those was a waste of money. The hasty generalization fallacy demonstrated

          2 replies 1 retweet 0 likes
        3. Dr Monya De MD MPH‏ @medjournalist 12 Dec 2019
          Replying to @medjournalist @gorskon and

          here is "antioxidants cause mortality " when this study showed that was not the case for several micronutrients. We haven't even discussed whether appropriate dosing was used.

          1 reply 0 retweets 0 likes
        4. Show replies

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