Anyway, my only point here is that sodium bicarbonate and pH manipulation may have a role in cancer treatment. More studies are needed to elucidate the role in detail. You can of course disagree with this, and, if so, let’s then leave it at that.
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Replying to @larshaakon @MedecinMadinina and
I do not disagree with that. I’ll await further studies.
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Replying to @DocBastard @MedecinMadinina and
Sounds like we agree then. Unfortunately, it is really hard to do studies on compounds like sodium bicarbonate as there is very little funding to be obtained to do the studies. This is a general problem plaguing off-patent drugs: https://www.economist.com/international/2019/03/02/repurposing-off-patent-drugs-offers-big-hopes-of-new-treatments ….
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Replying to @larshaakon @MedecinMadinina and
This is a very common anti-doctor and anti-science trope, that "natural" products are never studied because there is no money in it. That trope assumes that cancer researchers are solely in it for money, which is as ludicrous as it is insulting to their efforts.
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Replying to @DocBastard @MedecinMadinina and
I think you may misunderstand. Scientists study these compounds, but doing the costly randomized trials needed to get them approved for a new indication is near impossible given lack of funding/financial incentives. This is just a fact, nothing to argue about.
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Replying to @larshaakon @MedecinMadinina and
Then perhaps you can explain all the research currently being done on cannabis. You know, that plant They Can't Patent. Maybe you can explain the vitamin C in sepsis trial that was published last year. You know - vitamin C, that inexpensive ubiquitous molecule. You are mistaken.
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Replying to @DocBastard @larshaakon and
Faustman Labs working with a very cheap (something like $1 per dose) vaccine (BCG) as a treatment for type 1 diabetes. (https://www.faustmanlab.org/clinical-trials/ …)
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Replying to @MTL613 @larshaakon and
Very interesting. I await the phase II results.
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Replying to @DocBastard @MTL613 and
I admit I'm envious of your position, where you can always say "let's wait and see the results". Terminal cancer patients running out of treatment options and facing imminent death don't have that luxury. I suspect that is part of the reason our views differ.
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Replying to @larshaakon @MTL613 and
This is exactly the reason why snake oil salesmen profit off the desperate. They’re willing to try anything “just to see”. They sell false hope, which is cruel.
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Also, even if the evidence for alkalinization translates to humans in terms of improved survival, it is quite clear that at best it would only be an incremental advance.
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Replying to @gorskon @DocBastard and
How is that quite clear? Most new cancer drugs only provide incremental benefit, e.g. nivo/pembro in NSCLC - > ~2 months OS improvement. Yet they are celebrated as major advances. Do you think we should hold repurposed drugs to a different, and higher, standard?
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Replying to @larshaakon @gorskon and
Nivo/pembro gave 3 mo benefit in med OS in 2nd line vs. active SOC w/15-20% of pts alive & w/o PD for 2+ yrs; moreover, oncologists ever celebrated 2 mo as major advance. IMO, zealous advocacy for alkalinization is merely a litmus test of gullibility & lack of credibility.
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