I’m not 100% on board either, David -
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Oncologists think. Surgeons act. That's why.
Thanks. Twitter will use this to make your timeline better. UndoUndo
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What's the downside? Draw the prep creatinine, INR, Brca1/2. It's time to stop viewing these simple and cheap tests as privileged or special.
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Shouldnt we avoid paying for tests that likely wont influence treatment decison-making?
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Patient-advocate here. Even if marginally useful or of no use to patient, isn't this good info for children, grandchildren, other family members patient might have?
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Maybe but
@gorskon is also right that more tested women will want invasive surgery although the estimated risks of the BRCA-group get lower when you test and find more. 60-80% risk in lifetime will be adjusted to much lower.
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(BRCA2 is probably underdiagnosed, causing ER+ breast tumor at later age. Testing at 85 is probably not a good idea, but finding a BRCA2-mutation might be good for her daughter, sister, niece. You don't want them to get ovarian cancer) /1
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But... definitively, testing more means finding more. This will lower numbers of risk/incidence and the benefits on survival. On the other hand, with breastcancer screening women with low (!) risk get screening with much more harm. Maybe downsize to a high/moderate risk group /2
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