FWIW (and this is where I think philosophy can help with medicine), I believe evolutionary teleology, like most forms of teleology, often gets in the way of good science. Though useful as a hypothesis generating heuristic, it easily becomes a just-so story for pet theories. 1/2
That sounds more like the pCR rate for hormone receptor-negative/HER2-positive breast cancer treated neoadjuvantly with chemotherapy plus trastuzumab and pertuzumab, which can be as high as 50-60%.
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Actually Her2 pos pts have pCR rates ranging from 50-80% in modern Her2 directed regimens. Lower end for ER+ and upper end for ER negative. Triple negative pts in 2 large recent trials with 40% with standard 3rd gen regimen, increased to about 55% with addition of carboplatin.
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