Gautier Richard

@Gautier_Rich4rd

PhD, Computational biologist INRAE. Exbioinfo w/ Fascinated by vinyls & music

Rennes, France
biglink.to/gautier_richard
Vrijeme pridruživanja: lipanj 2019.
23 fotografije ili videozapisa Fotografije i videozapisi

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  1. Prikvačeni tweet
    14. lis 2019.

    Read the new Lab paper: guided reveal conserved regulatory on and autosomes despite extensive shuffling in . ⬇️Description in the comments below⬇️

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  2. prije 3 sata

    Les paroles sont belles, justes et pleines de vérité, mais le gouvernement n'en fera rien. Même en laissant les rues jonchées d'ordures et de rats le gouvernement reste inamovible et borné. Donc une tribune de plus ou de moins... C'est triste de délaisser la recherche comme cela.

    Au CNRS on se félicite de la sélection darwinienne des chercheurs, au Ministère on nous explique que le problème c'est l'attractivité de la recherche... Du coup, en a eu marre d'être pris pour des buses et on a pris la parole, nous les concernés 👇
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  3. proslijedio/la je Tweet
    3. velj

    "If you are not careful, you could end up spending an inordinate amount of time on things like Twitter" & many other nuggets of wisdom from the inimitable in his Q&A

    5 replies 47 proslijeđenih tweetova 199 korisnika označava da im se sviđa
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  4. proslijedio/la je Tweet
    3. velj
    Odgovor korisnicima

    Hey! We're actually halfway there and have an example of hg19 vs. hg19 here: For different genomes, there is an experimental solution. If you're interested, DM me or hop on our Slack channel ()

    1 proslijeđeni tweet 2 korisnika označavaju da im se sviđa
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  5. proslijedio/la je Tweet
    3. velj

    A permanent position of Research Scientist is open in our team. We are looking for a scientist with expertise in Fungal Genetics to study the role of sexual reproduction on adaptation to plant resistance

    1 reply 65 proslijeđenih tweetova 48 korisnika označava da im se sviđa
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  6. 3. velj

    articles introduced by . I hope this will become the norm in the next 10 years. This would improve papers SO MUCH and help meeting requirements.

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  7. 1. velj

    As outlined in his tweet there's also to parse HOMER motifs output. Really handy. I quitted using HOMER a while ago notably because of the pain of parsing the outputs.

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  8. 1. velj

    "marge" a R interface for "HOMER". Identify those motifs you like dearly and parse them easily within R with your favorite motif caller. REALLY nice!

    The aim of marge is to provide an R API to HOMER for the analysis of genomic data, utilizing a tidy framework to accelerate organization and visualization of analyses
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  9. proslijedio/la je Tweet
    1. velj

    retraite à 65 ans ancien système : 3089 euros net/mois retraite à 65 ans nouveau système : 2553 euros net/mois un grand merci à pour le partage des ses données et réflexions 2/2

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  10. proslijedio/la je Tweet
    1. velj
    Odgovor korisnicima

    Our bioinformatics guy said the same in this debunking of the paper:

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  11. proslijedio/la je Tweet
    30. sij
    Odgovor korisniku/ci

    And yet targeted methylation and demethylation assays can have sustained impacts on transcription level. Causality can be in both directions.

    1 reply 2 proslijeđena tweeta 8 korisnika označava da im se sviđa
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  12. proslijedio/la je Tweet
    30. sij

    First the chromatin opens, then the DNA methylation is lost. The chromatin opens because transcription factors (TFs) target those loci. TFs tell DNA methylation and nucleosomes what to do at cis-regulatory loci. Not the other way around. Your textbook needs a rewrite.

    Online Now: ATAC-Me Captures Prolonged DNA Methylation of Dynamic Chromatin Accessibility Loci during Cell Fate Transitions
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  13. proslijedio/la je Tweet
    31. sij

    Il y a 20 ans, la recherche sur les était un 'sous-domaine' peu financé de la virologie. La recherche fondamentale est "inutile" jusqu'à ce qu'elle devienne soudainement la chose la plus importante au monde. Imaginez si elle n'était plus du tout financée.....

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  14. 31. sij

    The main trick I learned from those slides

    Odgovor korisniku/ci @W_R_Chase
    Ahhh, how did I not know this? I spent ages writing a workaround function using grobs to get the same effect…
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  15. 31. sij

    Few tips and tricks for better plots! Check those slides ASAP: . Kudos to

    Slides from my talk are up on my site!
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  16. proslijedio/la je Tweet
    30. sij

    New Marchantia genome reassembly starring H3K27me3! Thanks to everyone who helped bring this together! Website with chromatin profiles, updated gene names:

    6 replies 45 proslijeđenih tweetova 105 korisnika označava da im se sviđa
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  17. 30. sij

    Hi people. I was doing comparative the other day and was day dreaming: will HiGlass support vs genome alignment matrices and their respective annotation plotting? One genome on the X, another one on the Y and the rearrangements in the central panel?

    1 reply 1 proslijeđeni tweet 4 korisnika označavaju da im se sviđa
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  18. 30. sij

    HiGlass in Jupyter Notebooks 😃! It's a great tool to visualize any genomic data interactively, but the main focus is on Hi-C matrices exploration.

    📣🐍Big new higlass-python release out last weekend! Create overlay and dataset ratio tracks directly in a notebook. Check out and for examples and more information.
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  19. proslijedio/la je Tweet
    29. sij

    is basically the Christmas morning of finding out about new packages. 🎁

    1 reply 12 proslijeđenih tweetova 71 korisnik označava da mu se sviđa
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  20. proslijedio/la je Tweet
    23. sij

    I’m thrilled to announce the publication of the quantitive proteomic profiling of the Cancer Cell Line Encyclopedia. The in collaboration with colleagues at Novartis and the Broad we measured the proteomes of 375 cell lines from various tumor lineages (1/13)

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  21. 29. sij

    I was discussing this with my brother who is a person. The community is awesome and is pushing people to not constantly reinvent the wheel! Also, what a pleasure to stumble upon a package that does more than what you were dreaming about. {UpSetR} comes to mind.

    The community is amazing, and new awesome stuff comes out ALL THE TIME. Keeping up can be exhausting, but exhilarating.
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