Eric Garr

@garrface

Postdoc @ Johns Hopkins. Behavior, brains, biking, and bagels.

Baltimore, MD
Vrijeme pridruživanja: ožujak 2016.

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  1. Prikvačeni tweet
    21. sij

    Excited to have this paper out! Chemogenetic inhibition in the dorsal striatum reveals regional specificity of direct and indirect pathway control of action sequencing. Publication➡️ Preprint➡️ Brief thread:

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  2. proslijedio/la je Tweet
    prije 22 sata

    If you live in Baltimore/Maryland's 7th Congressional District make sure you go out and vote in the primaries today! For the first time in Maryland you can register right at the polling place!

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  3. proslijedio/la je Tweet
    30. sij

    👉New research from our team shows that local and dynamic D2- to D1-neuron modulation in the striatum is necessary for reshaping goal-directed learning. Find out more in our study published today!

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  4. proslijedio/la je Tweet
    23. sij

    Paper out from huge effort by with help from superstar ugrads and the lab. How do all those habit measures go together and what’s the deal with phasic striatal activity?

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  5. 21. sij

    5. These are complex results 😅, but from these we offer some clear predictions for future experiments. Thanks to for the support and guidance!

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  6. 21. sij

    4. Inhibition of D2 neurons in DMS during training sped up sequence initiation during devaluation only when CNO was removed during test. We think this means that retrieving the knowledge necessary for goal-directed initiation requires the relative quiescence of this population.

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  7. 21. sij

    3. Inhibition of D1 neurons in DMS slowed sequence completion during devaluation only in rats given CNO during training and test. We think this population of neurons somehow participates in the prevention of goal-directed sequence completion that characterizes normal behavior.

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  8. 21. sij

    2. Speaking of devaluation, we generally replicate our previous finding that sequence initiation latencies are slowed during devaluation, but sequence completion latencies are unaffected. This pattern of data is violated when Gi-DREADDs are expressed in the dorsomedial striatum.

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  9. 21. sij

    1. We replicate an old finding—this time, in rats—that the dorsolateral striatum is crucial for learning an action sequence, and we show that the D2-expressing neurons are particularly crucial. Nevertheless, instrumental sensitivity to outcome devaluation remains intact.

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  10. proslijedio/la je Tweet
    18. sij

    Five years ago, ended legacy admissions. Today, the president of our university explains why in

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  11. proslijedio/la je Tweet
    15. sij

    The dopamine reward prediction error story further refined by in - its a distributional code, rather than a mean reward value, which they claim allows multiple possible outcomes to be captured in the signal

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  12. proslijedio/la je Tweet
    13. sij

    Ecstatic to share grad student and labmates' new paper online this morning. Showing endocannabinoid signaling collapse contributes to stress-induced anxiety and amygdalo-cortical plasticity

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  13. proslijedio/la je Tweet
    11. sij

    Very happy to have this out! Dopamine transients produce learning about antecedent cues, without making those cues valuable. Thread below summarizes our key points👇 Particularly proud as I spent experiment 3🤮 in a bin between squads while pregnant 😂

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  14. 10. sij

    I can’t count how many times I watched Neil’s instructional video “A work in progress” as a kid. He struck me as a person with an admirable sense of serenity. RIP

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  15. proslijedio/la je Tweet
    10. sij

    We have a new paper out: Isabell Ehmer uses SAPAP3 mutant mice in her PhD studies to explore the behavioral building blocks of compulsive behavior. This project is on habit formation in these mice.

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  16. proslijedio/la je Tweet
    8. sij

    Addiction is driven by excessive goal-directed drug choice under negative affect: translational critique of habit and compulsion theory

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  17. 4. sij

    neuro twitter: in this paper we report- behavior twitter: WE ALREADY KNEW THAT

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  18. proslijedio/la je Tweet
    2. sij

    Brains are amazing. Our lab demonstrates that single human layer 2/3 neurons can compute the XOR operation. Never seen before in any neuron in any other species. Out now in . Congrats Albert, Tim  & CO

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  19. proslijedio/la je Tweet
    30. pro 2019.

    Sensitivity of reaction time to the magnitude of rewards reveals the cost-structure of time

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  20. proslijedio/la je Tweet
    30. pro 2019.

    Neural reinforcement: re-entering and refining neural dynamics leading to desirable outcomes

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