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Prikvačeni tweet
Excited to have this paper out! Chemogenetic inhibition in the dorsal striatum reveals regional specificity of direct and indirect pathway control of action sequencing. Publication
https://www.sciencedirect.com/science/article/pii/S1074742720300137 …
Preprint
https://www.biorxiv.org/content/10.1101/796698v2 …
Brief thread:Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Eric Garr proslijedio/la je Tweet
If you live in Baltimore/Maryland's 7th Congressional District make sure you go out and vote in the primaries today! For the first time in Maryland you can register right at the polling place!
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Eric Garr proslijedio/la je Tweet
New research from our team shows that local and dynamic D2- to D1-neuron modulation in the striatum is necessary for reshaping goal-directed learning. Find out more in our study published today!https://science.sciencemag.org/content/367/6477/549 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Eric Garr proslijedio/la je Tweet
Paper out from huge effort by
@CregoAdam with help from superstar ugrads and the@mattmizumi lab. How do all those habit measures go together and what’s the deal with phasic striatal activity?https://www.jneurosci.org/content/early/2020/01/17/JNEUROSCI.1313-19.2019 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
5. These are complex results
, but from these we offer some clear predictions for future experiments. Thanks to @AndyDelamater for the support and guidance!Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
4. Inhibition of D2 neurons in DMS during training sped up sequence initiation during devaluation only when CNO was removed during test. We think this means that retrieving the knowledge necessary for goal-directed initiation requires the relative quiescence of this population.pic.twitter.com/jFLwjgI1Ct
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3. Inhibition of D1 neurons in DMS slowed sequence completion during devaluation only in rats given CNO during training and test. We think this population of neurons somehow participates in the prevention of goal-directed sequence completion that characterizes normal behavior.pic.twitter.com/uhzJUhVqEJ
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2. Speaking of devaluation, we generally replicate our previous finding that sequence initiation latencies are slowed during devaluation, but sequence completion latencies are unaffected. This pattern of data is violated when Gi-DREADDs are expressed in the dorsomedial striatum.
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1. We replicate an old finding—this time, in rats—that the dorsolateral striatum is crucial for learning an action sequence, and we show that the D2-expressing neurons are particularly crucial. Nevertheless, instrumental sensitivity to outcome devaluation remains intact.pic.twitter.com/6UNaMgiHmK
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Eric Garr proslijedio/la je Tweet
Five years ago,
@JohnsHopkins ended legacy admissions. Today, the president of our university explains why in@TheAtlantichttps://www.theatlantic.com/ideas/archive/2020/01/why-we-ended-legacy-admissions-johns-hopkins/605131/ …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Eric Garr proslijedio/la je Tweet
The dopamine reward prediction error story further refined by
@DeepMindAI in@nature - its a distributional code, rather than a mean reward value, which they claim allows multiple possible outcomes to be captured in the signalhttps://www.nature.com/articles/s41586-019-1924-6 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Eric Garr proslijedio/la je Tweet
Ecstatic to share grad student
@TheDavidJMarcus and labmates' new paper online@NeuroCellPress this morning. Showing endocannabinoid signaling collapse contributes to stress-induced anxiety and amygdalo-cortical plasticityhttps://www.sciencedirect.com/science/article/pii/S0896627319310906 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Eric Garr proslijedio/la je Tweet
Very happy to have this out! Dopamine transients produce learning about antecedent cues, without making those cues valuable. https://www.nature.com/articles/s41467-019-13953-1 … Thread below summarizes our key points
Particularly proud as I spent experiment 3
in a bin between squads while pregnant
https://twitter.com/MelissaJSharpe/status/1105509268520763394 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
I can’t count how many times I watched Neil’s instructional video “A work in progress” as a kid. He struck me as a person with an admirable sense of serenity. RIPhttps://twitter.com/vinniecolaiuta/status/1215753103602929664 …
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Eric Garr proslijedio/la je Tweet
We have a new paper out: Isabell Ehmer uses SAPAP3 mutant mice in her PhD studies to explore the behavioral building blocks of compulsive behavior. This project is on habit formation in these mice.https://www.sciencedirect.com/science/article/pii/S107474272030006X …
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Eric Garr proslijedio/la je Tweet
Addiction is driven by excessive goal-directed drug choice under negative affect: translational critique of habit and compulsion theoryhttps://www.nature.com/articles/s41386-020-0600-8 …
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neuro twitter: in this paper we report- behavior twitter: WE ALREADY KNEW THAThttps://twitter.com/dgonzales1990/status/1213287579447185409 …
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Eric Garr proslijedio/la je Tweet
Brains are amazing. Our lab demonstrates that single human layer 2/3 neurons can compute the XOR operation. Never seen before in any neuron in any other species. Out now in
@sciencemagazine. Congrats Albert, Tim@mattlark@YiotaPoirazi & COhttps://science.sciencemag.org/content/367/6473/83 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Eric Garr proslijedio/la je Tweet
Sensitivity of reaction time to the magnitude of rewards reveals the cost-structure of timehttps://www.nature.com/articles/s41598-019-56392-0 …
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Eric Garr proslijedio/la je Tweet
Neural reinforcement: re-entering and refining neural dynamics leading to desirable outcomeshttps://www.sciencedirect.com/science/article/pii/S0959438819301345 …
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