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  1. Prikvačeni tweet

    New video today! An overview of (nearly) everything that you’ve ever wanted to know about NAD+ and its related molecules, nicotinamide riboside and nicotinamide mononucleotide.

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  2. NOTE: the effect of alcohol on brain aging was only seen in daily or almost daily drinkers. Drinking alcohol daily (or on most days) was linked to ~5 months of accelerated brain aging compared to people who were the same chronological age but reported drinking less frequently.

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  3. Alcohol and cigarettes may accelerate brain aging. Every gram of alcohol consumed per day was linked to one week of accelerated brain aging and each year spent smoking one pack of cigarettes per day was linked to 11 days of accelerated brain aging.

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  4. Low-intensity exercise activated brain networks involved in cognition control and attention processing, while high-intensity exercise activated networks involved in emotion processing in male athletes. Both exercise intensities improved mood.

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  5. Sulforaphane from broccoli sprout extract improves fasting glucose and HbA1c (a marker for long-term blood glucose levels) in obese patients with dysregulated type 2 diabetes (12-week randomized placebo-controlled trial).

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  6. Get links to the studies and topic timestamps for my recent video on NAD+, NR, and NMN by clicking "timeline" on the episode page...

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  7. What do we know about the metabolic fate of nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) in tissues like the brain, liver, and muscle? In this clip, I talk about the 2018 paper which used isotope tracers in animals to find out...

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  8. Preliminary study found when oxytocin was administered as a nasal spray it led to a decrease in repetitive behaviors and fewer problems forming close social relationships compared to a placebo spray in men with autism spectrum disorder.

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  9. Stress caused hair to turn prematurely gray by activating noradrenaline, a neurotransmitter involved in the "fight or flight" response to stress, which caused the depletion of stem cells responsible for producing pigment in hair follicles (animal study).

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  10. Abdominal obesity is associated with fatal heart attacks and strokes independent of other risk factors (ie. hypertension and diabetes) and regardless of being treated with therapies that lower traditional risk factors such as lipid-lowering drugs.

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  11. Two compounds found in sunscreens and cosmetics called oxybenzone and propylparaben were found to cause DNA damage to breast cells in culture & in mice. A randomized controlled trial found that oxybenzone was absorbed above FDA's toxicological threshold.

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  12. Wow, these are beautiful! New high-resolution, full-color images of ice on mars via the ESA’s Mars Express Orbiter.

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  13. Taking fish oil supplements for 3 months was associated with higher semen volume, higher total sperm count, a larger testis size, and a higher free testosterone to LH ratio compared to men with no supplement intake.

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  14. proslijedio/la je Tweet
    17. sij

    America's most widely consumed oil causes genetic changes in the brain via

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  15. Preliminary findings suggest that women taking oral contraceptives have a smaller hypothalamus, a brain region involved in the regulation of the endocrine system, emotions, appetite, and body temperature. Larger studies need to confirm.

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  16. proslijedio/la je Tweet
    16. sij

    Quercetin intake significantly lowers blood pressure. 🧅🧅🧅 An analysis of 17 RCTs including 896 total participants found that quercetin significantly lowered both systolic BP (−3.09 mmHg) and diastolic BP (−2.86 mmHg).

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  17. Gut microbiome composition may be an important mediator of the positive effect of exercise on glucose metabolism and insulin sensitivity.

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  18. proslijedio/la je Tweet
    10. pro 2019.

    Randomized controlled trial shows 2.5 g/day of supplementation reduces Pro-aging factors (inflammation, oxidative stress) and increases even in young healthy students exposed to air pollution.

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  19. proslijedio/la je Tweet

    I'm excited to let you know that I'm doing a Reddit AMA on Tuesday, Jan. 14 @ 4 p.m. Eastern. Get your questions ready and I'll start exercising my fingers. It will be hosted on subreddit . I'll tweet specific link on the day of the .

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  20. Brake dust is a form of air pollution that consists of metal particles generated from mechanical abrasion from brakes that are small enough to be inhaled deep into the lungs. Brake dust may cause inflammation and alter the function of immune cells.

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