The preprint author is able to recover some of the deleted sequences from the cloud. It looks like they were originally uploaded on 15 February 2020.pic.twitter.com/az4tGvPpue
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The preprint author is able to recover some of the deleted sequences from the cloud. It looks like they were originally uploaded on 15 February 2020.pic.twitter.com/az4tGvPpue
Some background: The early sequences we ahve from Wuhan appear to be more distant from the putative bat ancestor of SARS-2, than virus sequences from outside Wuhan. Hypothesis: This is because early virus samples taken in proximity to Wuhan Institute of Virology were deleted.pic.twitter.com/XrjNf2i0iY
moar on the specifics of this odd problem.pic.twitter.com/t7Z4GigarZ
oh look. the mysteriously deleted sequences are also phylogenetically closer to the putative bat ancestor than the Seafood Market sequences.pic.twitter.com/qbvbwTebW9
relative distance to RaTG13, the closest relative of SARS-2. You see the seafood market sequences are all late; the deleted Wuhan sequences are earlier. The Guangdong patient infected before Jan 5 among the earliest of all.pic.twitter.com/EtUUcRtoYk
SARS-2 got away from Chinese authorities with the outbreak at the Huanan Seafood Market in Wuhan. This was the event that attracted international attention. The seafood market viruses were inevitably sequenced, while other, earlier virus samples from Wuhan were suppressed.
This created the obvious problem, that virus sequences from outside Wuhan (not only from elsewhere in China, but elsewhere in the world) seemed to be phylogenetically prior to the Wuhan viruses. Because only the seafood market samples were known, and that was a late outbreak.
Early SARS-2 sequences were deleted to obscure the origins of the virus at the Wuhan Institute of Virology.pic.twitter.com/pTYbTcTRps
Now, some caveats. This is a really reader-friendly paper, with extensive, accessible discussion of the origins problem. And it's already been written up in the New York Times. I don't know, feels a little weird.https://www.nytimes.com/2021/06/23/science/coronavirus-sequences.html?action=click&module=Top%20Stories&pgtype=Homepage …
NYT: the establishment's favourite. The story claims leak, or zoonotic. No mention of possible intentional release. Whoever can prove the origins has an invaluable bargaining chip.
I also worry that there may be an attempt here, to open the door to finding more „deleted“ sequences that will then prove literally anything they want.
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