Yeast have a structure called the plasmid which is a circular piece of DNA that can indefinitely replicate and exists separately and independently from organism’s main DNA found in its chromosomes. The plasmid can be easily extracted, genetically modified, put back into the cell.
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Yeast also have clustered regularly interspaced short palindromic repeats (CRISPR) from prior infections from bacteriophages. Using a Cas9 nuclease to create a double-stranded break in the yeast’s DNA at CRISPR sites, we can insert the ACE2 gene through homologous recombination.
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It takes many attempts to get it right, especially if the yeast does non-homologous end joining which can destroy the modified gene. But once you have a successful run, yeast reproduces exponentially in huge vats which is how Big Pharma makes insulin yet sells it for high prices.
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I know this all sounds complicated for those who haven’t studied it. But it’s actually fairly simple and the technology has been around for several years. Someday we need to teach this in high school and let students make their own genetically modified yeast in biology class.
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And yes, it would be pretty ironic if the coronavirus can be treated or cured using the same species of yeast that also makes Corona beer.
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I’m currently in the hospital… Did not know anything was wrong but people insisted I go. I have pneumonia and the flu… From stress I have aorta aneurysm...These last few years have taken their toll! Hope the coronavirus keeps its distance from all of us!
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Hope you are on the road to recovery.
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...yes but how to deliver it.
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Specifically fermented beverages aka beer. It’d be ironic if Corona the beer company took the lead on this.
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I think I would patent this ide instead of putting it on Twitter
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Čini se da učitavanje traje već neko vrijeme.
Twitter je možda preopterećen ili ima kratkotrajnih poteškoća u radu. Pokušajte ponovno ili potražite dodatne informacije u odjeljku Status Twittera.