#Genome #editing w/o double strand breaks or donor #DNA??? Not magic, it's a #Cas9 #nickase fused to a #reverse transcriptase & a #guide #RNA ("pegRNA") that guides Cas9 to its #target AND serves as template for the #sequence to integrate in the DNA! Boom!
https://www.nature.com/articles/s41586-019-1711-4 …pic.twitter.com/aeAaH4bDnZ
18:43 - 1. stu 2019.
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