This week's Commonplace post is about neuroplasticity, and why it's mostly a useless idea: commoncog.com/blog/neuroplas
But the general principle is actually what is more interesting to me: you want to grok ideas at the right level of abstraction. Not too high, and not too low.
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It sounds like it might be more fruitful to mine the very rich, very large, and very deep literature on spaced repetition, in order to investigate all the ways spaced repetition has failed over the years. gwern.net/Spaced-repetit
I'd say that LTP is too low level to be useful.
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