Going to skim the first few chapters; just a lay-friendly review of basic genetics. Figures are excellent though.pic.twitter.com/50YfuvUV1b
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Surely this varies by radiation type? Eg imagine ingested alpha emitters are pretty effective mutagens relative to gamma emitters (??)pic.twitter.com/M5YTMC4NXf
Breaking for today, but going to keep going soon. Expect the tastiest parts yet to come.
most mutations are cell divisions, and sperm divides much much more than ovules because that's, like, The Whole Deal With Sex Differences want eugenic measures against mutation load? get a bloody universal sperm bank. book discusses it later
another fun implication of"most mutations coz divisions" you know what takes a lot of cell divisions? turning a flimsy stem cell(zygote)into an adult with bazillion of cells many/most cancer mutations are not due to mutagens or heredity, just developmenthttps://twitter.com/SilverVVulpes/status/957779269597483008 …
Ugh Yeah I was thinking about this Like--blastocyst-phase "autosomal" mutations, tons of opportunities for this Eeeesh
idea is that all your loved ones, cat included, are full of proto-cancers and the real deal is older age and other risks factors creating selection *for* them so it spreads most knockouts of crucial genes being 0.1% of your cells is ok, cancer is bad because it goes darwinian
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