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eigenrobot's profile
eigenrobot
eigenrobot
eigenrobot
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eigenrobot

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eigenrobot.substack.com
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    3. american biologist‏ @95thoughts May 7
      Replying to @geoliberal @RobertB41188300 and

      well said yeah CRISPR and the epigenetic modification system would be two distinct examples of lamarckian processes i could talk your ear off about the second butpic.twitter.com/kg2tKHv0HU

      2 replies 0 retweets 2 likes
    4. Alan Forrester‏ @alan_forrester May 9
      Replying to @95thoughts @geoliberal and

      https://conjecturesandrefutations.com/2021/05/09/on-alleged-lamarckism/ …

      1 reply 0 retweets 1 like
    5. american biologist‏ @95thoughts May 9
      Replying to @alan_forrester @geoliberal and

      I can see how you would define away CRISPR as non-Lamarckian by virtue of the knowledge existing elsewhere and integrated into the bacterial genome- this feels a bit like moving the goalpost from Lamarck to Deutch’s definition of Lamarck - but I’ll play

      1 reply 0 retweets 0 likes
    6. american biologist‏ @95thoughts May 9
      Replying to @95thoughts @alan_forrester and

      Regardless, there are unambiguously Lamarckian processes in the vertebrate immune system; new knowledge is literally created to generate new antibodies in B cells via somatic hypermutation; good B cells proliferate and persist as memB. The way they do this;pic.twitter.com/89QZqX7mUD

      1 reply 0 retweets 0 likes
    7. american biologist‏ @95thoughts May 9
      Replying to @95thoughts @alan_forrester and

      leads directly into my next point; to call methylation insignificant is to misunderstand how we define a nucleotide. After all, the only difference between C and U is deamination; and the only difference between U and T is a methyl group- and so the methylation status of that Cpic.twitter.com/zMXAn6OT7R

      1 reply 0 retweets 0 likes
    8. american biologist‏ @95thoughts May 9
      Replying to @95thoughts @alan_forrester and

      Literally determines the outcome of deamination. This has implications for how cytosine methylation is an engine of the lamarckian process created by the epigenetic modification system... but it’s too soon for me to get into details as I’ve stated

      1 reply 0 retweets 0 likes
    9. american biologist‏ @95thoughts May 9
      Replying to @95thoughts @alan_forrester and

      So this is process is not “setting the thermostat on your boiler”, it is a literal change in the material composition of the boiler itself

      1 reply 0 retweets 0 likes
    10. Alan Forrester‏ @alan_forrester May 9
      Replying to @95thoughts @geoliberal and

      Making intellectual progress would require an extended piece of writing with actual quotes and arguments. You haven't done this and I'm not interested in just shooting the shit. glhf

      3 replies 0 retweets 0 likes
      eigenrobot‏ @eigenrobot May 9
      Replying to @alan_forrester @95thoughts and

      dude if you disagree you can just disagree without being a jerk

      10:53 AM - 9 May 2021
      • 1 Like
      • american biologist
      0 replies 0 retweets 1 like

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