welp that settles it as far as I'm concerned absurd it took this long for someone to do monkey studies on thishttps://twitter.com/davidrliu/status/1263960572032430080 …
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>practically speaking, if you can't see anything in a small n animal study, nobody is gonna want to give you more animals, or god forbid go into humans AaAaaagghahhhrrrghhggghhggghhh
"if you don't see an effect in a massively underpowered experiment in a population quite different from the one where the treatment is intended to be applied we stop experimenting" WHO IS RESPONSIBLE FOR THIS PARADIGM
the point is that it is a controlled animal study where we don't have all the confounders and variance we get from observational studies in humans what we expect/hope is incredible, blazing in vitro results! > really good animal results > statistically significant in humans
w HCQ we have kinda ok in vitro > nothing in animals > nothing much in humans
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