genomics question 1. there are huge numbers of SNPs thats tricky 2. there are 23 or so chromosomes 3. roughly, chromosomes can change by mutation or by recombination 4. recombination is relatively infrequent for adjacent sequences 5. mutation is relatively infrequent
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OHOHOHOHO looks like ive just reinvented something (badly) again just like that time i worked myself up to reinventing shitty cryptographic hashes someday its gonna be something Newhttps://twitter.com/arguablywrong/status/1202803515782914048?s=19 …
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seriously tho
@arguablywrong's explanation above is great and worth readingShow this thread
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wouldn't work without serverless quantum annealing on a decentralized blockchain
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Yeah, the term you're looking for here is haplotype: https://www.genome.gov/genetics-glossary/haplotype … Some of what you suggest is possible, but tricky. Key issue is that building haplotypes is pretty hard with current sequencing tech.
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(for a single individual, that is - gets a lot easier with populations, and a *lot* easier with a family of known relatedness)
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Geneticists use a technique related to the idea you described called Extended Haplotype Homozygosity to estimate the age of certain mutations/adaptations from the length and frequency of these identical segments (they decay over time via mutation&recombination).
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EHH and related techniques can be used to reconstruct the spread of adaptations and their selective strength, and to make inferences about their origin.
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