Considering the fact that virtually ALL of the papers on GD since around 2000 have been of people who experienced dysphoria & chosen to transition with NO controls on those who did not, they contain the same bias that you're condemning in Littman.
I had lifelong discomfort with my body, as well as psychiatric symptoms including depersonalization that interfered with my quality of life. Like other patients with similar symptoms, they resolved with treatment.
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If there's a problem with false positives- with patients who aren't helped by the treatment receiving the treatment, I could not be more supportive of efforts to better identify which patients will be helped and which won't.
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