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PRE AND POST EXPOSURE PROPHYLAXIS for the attendants and family members of a covid patientpic.twitter.com/lkKs51eCuk
AIIMS INDIA ENDORSED IVERMECTIN IN COVID this is ground breaking news for medical fraternity of indiapic.twitter.com/TPRcxleqeQ
FEW THINGS NEVER CHANGE....... rather they grow more strongerpic.twitter.com/TjSrPHH6ry
EARLY HOME BASED TREATMENT FOR MILD TO MODERATE COVID CASESpic.twitter.com/q3zKSXdy0p
NOTE:- HOME TREATMENT FOR MILD CASES ANYONE FROM IVERMECTIN-12 OR HYDROXYCHLOROQUINE-400, CAN BE USED
SECOND COVID WAVE IN INDIA, EXCESSIVE ANDROGENIC EXPRESSIONS AND NEWER STRAINS a thread on second wave in indiahttps://twitter.com/drakchaurasia/status/1384455528349196289?s=19 …
nobody other than a physician can understand, what this new strain is. and what this strain needs to be mitigated. age 32yrs spO2 95%, despite of all previous regeme, dropped to spO2 82%. after 7 days of desperate efforts, today he recovered to 97%. this is 2nd wave of india
1/2 today, this pt is send to home in satisfactory conditions. follow up needed at least 3 weeks. (the tentative protocol used in this pt, I'll post after feedback from few more pts.)
grossly stating, to mitigate fast progression of pulmonary conditions in this pt, drugs used, *spironolactone+frusemide *dutasteride+tamsulosin *inositol-niacin along with other routine antivirals and anti-inflammatories
REVISED COVID TREATMENT- 1 (this thread is an integrated part of previous covid guidelines, in perspective of newer strains) *tentative treatment to be started from first symptoms *treat mild case, assuming it as moderate one *speed of starting early treatment is the keypic.twitter.com/Q5J9PWRXUd
REVISED COVID TREATMENT- 2 *at least two antivirals to be used in full dosage *treatment for pneumonitis/hypoxia to be started prophylactically, before starting symptoms *NAC, GLUTATHIONE, SPIRONOLACTONE to be started from beginningpic.twitter.com/TMI8ghUs2d
REVISED COVID TREATMENT- 3 (sample) *IVM/ HCQ/ FEVIPIRAVIR/ NITAZOX *AZM/ doxy/ clarithro/ cefuroxim-cv/ *ibuprofen/etoricoxib/ aceclo+ bromelin/tryp-chymo *levocetrizine+montelukast *deflazacort/ dexamethasone/ budesonide inhaled *cyprohep/indomethacin *famotidine/ rabeprazolepic.twitter.com/tOXzJiEe10
FINAL TAKEAWAY OF THIS THREAD IS *JUST START TREATMENT WITHOUT DELAY *AND CONSIDER INVESTIGATIONS AFTER STARTING TREATMENT (i do admit, there are many missing in these guidelines, but our docs and colleagues will use their own wit n wisdom to fill gaps)https://twitter.com/drakchaurasia/status/1383827850332045319?s=19 …
PCM *paracetamol is toxic to liver and this is an established fact *equally important fact is, that no NSAID is capable to provide desirable analgesia without low dose supplement of paracetamol *low dose paracetamol use over a period of 1- 2 week, is harmless, add SAMe if needed
the standard recommended dosage of IVM are IVERMECTIN 12mg twice daily ×3 days MY RECOMMENDATIONS ARE IVERMECTIN- 12mg once daily ×7days FOR SECOND WAVE IVERMECTIN- 12 mg twice daily ×7 days OR IVERMECTIN- 12 mg once daily ×7 days + HCQ- 400 once daily ×7 dayspic.twitter.com/WrLiHZKQOq
MY PRESCRIPTION TODAY today's highlights *IVM *HCQ *AZM *FLUVOX *DOXY *SPIRO+FRUSEMIDE *DUTASTERIDE *PIROXICAM *NIACIN- NF https://twitter.com/SoftwarImmortal/status/1387353508379185153?s=19 …pic.twitter.com/o1f3aRARqu
COVAXIN FROM INDIA the inactivated virus vaccine "Covaxin found to neutralise '617 variant' of Covid, says US expert"https://m.tribuneindia.com/news/nation/covaxin-found-to-neutralise-617-variant-of-covid-19-dr-fauci-245374 …
PLEASE *i have kept an eye on fatalities occurred, despite of taking proper HCQ prophylaxis in 2020 PROUDLY SAYING, NONE *in covid 2021, we need a fine tune in dosage and protocols, in older ones.but i assure everybody listening, DRUGS ARE STILL GOLDSTANDARD please watch updatespic.twitter.com/rjaZ5oXxZN
MUCORMYCOSIS- ITRACONAZOLE, THE PROMISING ANSWER TO A AGONISING PROBLEM itraconazole has in vitro proved anti coV2 activity too https://cmr.asm.org/content/18/3/556 …
IVERMECTIN- SAFETY OF HIGHER DOSAGES EC-50 400- 600mcg/kg body wt/dayhttps://twitter.com/__ice9/status/1352580058481876993?s=19 …
WE NEED REINFECTION if delta lineage is, what it is known for R2-3 virus+mild non-lethal illness *it is best to get reinfected from it *it'll refresh past natural immunity *it'll strengthen incomplete immunity from vacs *it'll complete suboptimal immunity from past infection
DELTA LINEAGE- HOW PATHOGENIC IT IS world data show against it "You need to study a few hundred patients who are sick with this condition and variant and find out whether they are at greater risk of greater disease than ancestral variant," Dr Kang said.https://www.bbc.com/news/world-asia-india-57564560.amp …
LIST OF RETRACTED COVID19 STUDIES noticeable is that how many good studies were retracted merely in reaction to fake retracted studies 1/1 https://retractionwatch.com/retracted-coronavirus-covid-19-papers/ …
1/2 RETRACTED IN RESPONSE TO A FAKE RETRACTED STUDY "Rx Response to HCQ,Lopinavir/Ritonavir,and Antibiotics for Moderate COVID:A First Report on Pharmacological Outcomes from South Korea” preprint posted May 18, 2020 in medRxiv,and withdrawn June 14, 2020"https://www.medrxiv.org/content/10.1101/2020.05.13.20094193v1?versioned=true …
1/3 this is one small example, how few fake studies, damaged ongoing covid studies, and affected fight through good effective drugs. and, how in a graded organised manner good drugs were discouraged and outcome of pandemic was made worse.
ADE MEDIATED VIRAL ENTRY INTO CELL IS ONLY BY ENDOCYTOSIS. AND IT CAN BE PREVENTED BY HCQ hcq elevates pH of endosome, blocking this route When an antibody to a virus is unable to neutralize the virus it is forming sub-neutralizing virus-antibody complexes. 1/1pic.twitter.com/9tAptfXv6L
1/2 "Upon phagocytosis by macrophages or other immune cell such complex may release the virus due to poor binding with antibody. This happens during the step of acidification of phagosome before fusion with lysosome"
INDIA NEEDS KEEPING R VALUE BELOW 1.0 presently having R 0.95 critical times to bring it still low "Mumbai and Pune at R counts of 1.09 and 1.13, respectively,Chennai is hovering at 0.96 and Kolkata is at 0.95 while Delhi is at 0.89 and Bengaluru at 0.88"https://m.economictimes.com/news/india/worry-has-a-new-variant-r-count-of-covid-hovering-around-the-key-1-mark/articleshow/88133883.cms …
MAIN T CELL ANTIGEN IS 'N', NOT 'S' S directed vacs don't confer T cell memory "main T cell antigen is N, not S. Not to mention all the other proteins, some of which are much more conserved"https://twitter.com/gerdosi/status/1468522764575416320?t=xodtWJVM5_l-JT0tDkPG_g&s=09 …
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