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Joseph D'Orazio
@dorazepam
Emergency Medicine, Medical Toxicology, and Addiction Medicine. #FOAMed #TRUSTClinic __ 🦅🦅🦅✌️☝️✋ #CureAngelman
Philadelphiaangelmangabriel.orgJoined March 2010

Joseph D'Orazio’s Tweets

In the 1950s, CEOs were paid 20x more than the average worker. In the 1980s, CEOs were paid 59x more. In 2009, CEOs were paid 180x more. Today, CEOs are paid 399x more than the average worker. We must put an end to this rampant greed and inequality.
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Very few mainstream publication reporters were on the advent of xylazine in the drug supply as early and as persistently as — with her brand of empathy and exploring evidence, not sensationalizing. Her latest. Give it a read.
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In the last few years, the animal tranquilizer xylazine has made its way into nearly all of Philadelphia’s opioid supply. with a primer on the problem, and how drug users, advocates, and health officials are trying to address it ⤵️
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So excited for the next chapter for and for Dr Healy ! The transition has been seamless thanks to Temple leadership and departmental stability. Dr Healy is a great leader for our program.
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We are thrilled to announce a transition in our leadership — DR MEGAN HEALY is officially the new PD for the TempleEM residency program! We cannot thank Dr J Ufberg enough for his work and support as our outgoing PD. We are so excited that he is staying close as one of our APDs!
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“I’d wake up in the morning crying because my arms were dying.” Known on the street as “tranq dope,” the mix of fentanyl and an animal sedative is deepening addiction, baffling law enforcement and causing wounds so severe that some result in amputation.
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So you are 96% likely to walk/sit by/ breathe the air of someone infected while flying. You can choose to rely only on air filtration (which helps on a running plane- NOT in TSA, boarding, etc), but this ends debate on utility of N95 use during air travel.
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Sharing again. Our Overdose Prevention team reports a surge in ODs in Kensington. We can't be sure yet if the surge is due to nitazenes but certainly suspect it. Remember: -Carry extra Narcan. Nitazenes are 40x stronger than fentanyl. -Fent test strips cannot detect nitazenes.
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Yesterday @PHLPublicHealth distributed an alert stating that nitazene analogs have been detected in Philly's illicit drug supply. Nitazene analogs are synthetic opioids up to 40x stronger than fentanyl. Carry extra #Narcan. Remember — Narcan freezes at temps below 5°F (-15°C).
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This time, tomorrow! We hope to see you at #addiction medicine rounds with Dr. Joseph D'Orazio, speaking on #xylazine toxicity, withdrawal management, and treatment implications.
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What is the human pharmacology of #xylazine? How do you recognize signs & symptoms of a xylazine-involved #overdose? Of xylazine withdrawal? 🌟 Registration Now Open🌟for #addiction med rounds on 11/22 12-1pm w/ Dr. Joseph D'Orazio (@templemedschool) 🔗yalesurvey.ca1.qualtrics.com/jfe/form/SV_1F
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From what I’m told, showing up more frequently in Philadelphia. Thanks !
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🚨 New #Synthetic #Opioid Identified in the U.S. 🚨 N-Desethyl Isotonitazene has emerged as the next new #nitazene analogue (on its own, not as a metabolite of isotonitazene). More details ⬇️ ⬇️ 👀 Be on the look out for an upcoming Public Alert ‼️ 📄: cfsre.org/images/monogra
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What’s the cause of xylazine associated wounds? Looking at animal experience may give us a window into understanding this but more research is needed. I would love to hear from people with experience using xylazine in animal research and see biopsy results.
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Let's be clear. Eli Lilly should apologize for increasing the price of insulin by over 1,200% since 1996 to $275 while it costs less than $10 to manufacture. The inventors of insulin sold their patents in 1923 for $1 to save lives, not to make Eli Lilly's CEO obscenely rich.
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We apologize to those who have been served a misleading message from a fake Lilly account. Our official Twitter account is @LillyPad.
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1/As I said to the new Guideline on opioids is better, and I also disagree with key parts But the #1 point: protection for patients with long-term pain depends on 3 agencies NOW taking action: (DEA) and
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CDC issues new opioid prescribing guidance to replace 2016 version that doctors and patients say led to a crisis of untreated pain. For prescribers who are navigating the thorny issue of treating pain, the 100-page document provides a roadmap. n.pr/3G04nqH
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