Denis Jabaudon

@denisjabaudon

Developmental neurobiologist, neurologist, & evo-devo aficionado

Geneva, Switzerland
Vrijeme pridruživanja: lipanj 2013.

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  1. 1. velj

    For a songbird to become a good singer, its (genetically-determined) singing style must match that of its tutor. Cool example of gene-envir interactions. And a solace for so many of us karaoke singers out there.

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  2. 30. sij

    3/3 Con: scrambling the temporal sequence of experiments after results are known involves pseudo-hypotheses and misrepresents the discovery process. This might affect how future studies are conducted. i.e. can't shuffle the experimental fossil record. What are your thoughts?

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  3. 30. sij

    2/3 Pro: Streamlined, post hoc aligned storylines are easier to understand and remember and hence to one day experimentally build upon. i.e. we're not historians, so that’s ok.

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  4. 30. sij

    In exploratory science, to which extent should scientific findings be communicated through post hoc constructed narratives? (1/3)

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  5. 29. sij

    Deletions or duplications of the 22q11.2 chromosomal region both result in similar core phenotypes (heart defects, velopharyngeal insufficiency, urogenital abnormalities). See e.g. I find this so odd... Any other examples?

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  6. proslijedio/la je Tweet
    11. velj 2019.

    Every other year I re-read Scarr & McCartney (1983) for my grad developmental psych class. There are *so* many good parts in this paper, I'm going to give you some of my favs.

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  7. 27. sij

    Patrik Versteken from visiting today, providing an impressive coverage of Parkinson's disease research, from sleeping flies to human neurons in a dish. We need many many models to build the picture of complex diseases.

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  8. 27. sij

    Media attention can be an effective form of science communication but should be an avenue for scientific, rather than self, promotion.

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  9. 25. sij

    The issue of "pseudoreplication" is interesting: basically, transplanting feces of a single patient into multiple mice should count as a single N. Is that also true for all patient-derived biol, such as iPS and organoids then? Are multiple HeLa cell exps "pseudoreplication"? 2/2

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  10. 25. sij

    Interesting and careful perspective on the limits and caveats of current microbiome research. Likely applies to all new fields, when excitement +++ and scientists and editors rush to publish. 1/2

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  11. 24. sij

    Inspiring talk by here in Geneva today, even featuring a gyrencephalic cactus as intro slide.

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  12. 24. sij

    Snake venom gland organoids. This is so badass it even looks like one...

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  13. 24. sij

    Oh, with a snapshot of the key figure here

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  14. 24. sij

    Different cortical areas have different maturation speeds; mPFC is a late bloomer. Here, early postnatally, GABAa activation is excitatory in the mPFC but already inhibitory in S1 (links with KCC2 expr). Hence (perhaps) an area-specific effect of GABA.

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  15. 23. sij

    Beautiful talk by here at our Geneva . Objects, faces, bodies, experimentally broken down into their lowest dimensions and then re-mapped onto n-dimensional manifolds to ID functional neuronal network. An amazing tour de force.

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  16. 23. sij

    Oh no, why tweet that only after Christmas...??

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  17. 23. sij

    When I saw this schematic on 's desk, I thought she had come up with a new sectioning approach or smthing. But no, it's just a new recipe for a cake. Oh, but contains agar agar, so wasn't fully off-topic 😂🤓

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  18. proslijedio/la je Tweet

    Come join us in Sicily at the 7th annual cortical development meeting!

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  19. 22. sij

    Synaptic NMDAR-mediated transmission decreases with age in adult human synapses. This may reflect a preferential decrease in the (slow decay kinetics) GluN2B subunit-containing NMDARs, which let more Ca2+ (and memories) in. So use 'em while you can...

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  20. 21. sij

    Interspecies differences in cell cycle length (mouse-human) seem to reflect Δ in pace of protein degradation rather than in protein synthesis. Elegant mechanistic dissection by . Retweeting this as the pre-print has been updated.

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