Debora Marks

@deboramarks

Mission: develop AI for design of biological interventions for environment and human health  (to save the world)

boston
Vrijeme pridruživanja: rujan 2008.

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  1. proslijedio/la je Tweet
    23. sij

    Important paper out on via 96% sequence identity to a bat ~80% sequence identity to SARS ~95% AA sequence identity in 7 conserved replicase domains to SARS uses the same cell entry receptor, ACE2, as SARS

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  2. 24. sij

    PS: 99.99% proteins are outside CASP

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  3. 24. sij

    : does enalapril work?

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  4. 24. sij

    : Anyone notice two ‘accessory’ ORFs not annotated ? Orf13 (aka 9b) (28284:28577) and Orf14 (28734:28955) ~90% to BAT SARS 2017

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  5. 19. sij

    That’s why we have to find new ways to infer homology or similarity - and new ways to find structural plasticity

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  6. 18. sij

    Predicting structure of designed protein is not harder than natural ones esp when designed have encoded the rules we know - take care with logic there folks ..

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  7. proslijedio/la je Tweet
    18. sij
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  8. 18. sij

    Ah .. that’s why I’ve always been such an unhappy person ..

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  9. 18. sij

    Thanks all who responded and also thanks to for apologizing.

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  10. proslijedio/la je Tweet
    17. sij

    Thanks. I'm surprised that there is no analysis of the effect of the depth of the alignment and generalisability to proteins with fewer homologues. How much does the method learn something general and how much is based on a more robust extraction of dist distributions from MSAs?

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  11. 17. sij

    I need to stop moaning and get on with bigger challenges that are more important

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  12. 17. sij

    A machine can now keep livers alive outside the body for a week - MIT Technology Review

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  13. 17. sij

    because didn’t credit should I

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  14. proslijedio/la je Tweet
    17. sij
    Odgovor korisniku/ci

    Is key ingredient in evolutionary couplings ? As in first successful 3D folding

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  15. 17. sij

    Another link

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  16. proslijedio/la je Tweet
    17. sij

    Total self advertisement - feeling bitter and twisted of course :)

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  17. 17. sij

    Total self advertisement - feeling bitter and twisted of course :)

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  18. 17. sij

    Disappointed that didn’t get references quite right- first was

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  19. proslijedio/la je Tweet
    9. sij

    Looking for an internship this summer? Apply for the Systems Biology Internship! It's paid, we organize your accommodation, and you'll get to work with really cool people. Deadline Feb 9.

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  20. 11. pro 2019.

    Organized by MiA folks and friends from Broad and a large number of others ! See link for full list and schedule

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