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Daniel Bryan Goodman proslijedio/la je Tweet
We are back with
@OctantBio's OnDeck Seminar Series. This Thursday evening,@lexrovner, founder of@64minusX (YC S18), will talk about the tech behind the co, and where they are headed. Food at 5:30; talk at 6:00. Please sign up herehttps://tinyurl.com/ondeckfeb20Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Daniel Bryan Goodman proslijedio/la je Tweet
I was really excited when I saw some positive events in my dot plot. So I gated them and displayed a new dot plot next to the original one to look into this further, but the events disappeared! I was gating the laptop screen dirt.
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Daniel Bryan Goodman proslijedio/la je Tweet
Nice PhIP-Seq study from DeRisi & Anderson Labs: Identification of novel, clinically correlated autoantigens in the monogenic autoimmune syndrome APS1 by PhIP-Seqhttps://www.biorxiv.org/content/10.1101/2020.01.20.913186v1 …
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Daniel Bryan Goodman proslijedio/la je Tweet
This has been a really fun one! challenging the wisdom that one needs a lot of data to do ML guided biodesign. In fact, if you have to choose, think about getting HQ small-N data aligned w your endpoint, vs HT proxy data. low-N ML now helps you succeed w the former!https://twitter.com/grigonomics/status/1220768850834284544 …
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Daniel Bryan Goodman proslijedio/la je Tweet
5-year predictions 1. Active learning in biology - confluence of design (ML), build (large-scale dna synth/edit), and test (multiplexed assays) allows massive scale for exploring new function. Will require programmatic ways to explore that space. Expmnts no longer limiting. [1/n]https://twitter.com/AGoulburn/status/1220038803181752320 …
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Daniel Bryan Goodman proslijedio/la je Tweet
It's time to replace λBeta in MAGE, DIvERGE and ssDNA recombineering! By analyzing 100s of proteins, we have identified 2 that allow E.coli oligo-recombineering with up to 50% efficiency, increase multiplexability + allow MAGE in P. aeruginosa https://www.biorxiv.org/content/10.1101/2020.01.14.906594v1 …pic.twitter.com/2h1yPjQbia – mjesto: Harvard Medical School New Research Building
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Daniel Bryan Goodman proslijedio/la je Tweet
Innovative analysis of a continuum of single-cell expression using Pareto task inference. Fibroblasts trade-off several biological functions in the tumor micro-environment.https://twitter.com/shouval/status/1216983961374797831 …
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Daniel Bryan Goodman proslijedio/la je Tweet
An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD+ imbalance https://go.nature.com/2u0feh1 pic.twitter.com/R9ZNyxuwy0
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Daniel Bryan Goodman proslijedio/la je Tweet
Assistant Prof. Vs. Full Professor getting a grant.pic.twitter.com/mVLJJcCeHn
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Daniel Bryan Goodman proslijedio/la je Tweet
We find granzyme positive CD8 T cells next to degenerating neurons in hippocampi of Alzheimer’s patients. A smoking gun and a dead body but more work will be needed to prove that that gun killed the neuron. More here https://www.nature.com/articles/s41586-019-1895-7 … and here …https://scopeblog-stanford-edu.laneproxy.stanford.edu/2020/01/08/suspicion-why-are-virus-targeting-immune-cells-sniffing-around-alzheimers-patients-brains/ …
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Daniel Bryan Goodman proslijedio/la je Tweet
It seems just a matter of time until we fully conclude that the adaptive immune system is keeping tabs on nearly every healthy and diseased state. How many semi-dormant viruses do we all have by now in various tissues? Great find
@wysscorayhttps://www.nature.com/articles/s41586-019-1895-7 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Daniel Bryan Goodman proslijedio/la je Tweet
Newest work from
@goGUrtecho and@kiminsigne from the lab on comprehensively exploring E. coli promoter function. Blog post/tweetstorm coming on this work, but in the meantime if you have comments/thoughts, we plan on submitting in the next few weeks.https://twitter.com/goGUrtecho/status/1214259097391882242 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Few things get molecular biologists more riled up than restriction enzyme pronunciation.
@NEBiolabs just walked into a minefield.https://twitter.com/NEBiolabs/status/1213075047876825089 …
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Daniel Bryan Goodman proslijedio/la je Tweet
2020 will be the decade of cell therapy and genome engineeringhttps://twitter.com/BLLPHD/status/1212454696381751296 …
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These beetles do not exist.https://www.cunicode.com/works/confusing-coleopterists/#StyleGAN …
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Daniel Bryan Goodman proslijedio/la je TweetHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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Daniel Bryan Goodman proslijedio/la je Tweet
1) Create a community around obsessive enjoyment of something 2) Community becomes productive & high status 3) Wages & status attract careerists to the field 4) Signaling games arise to separate careerists from real obsessives 5) Careerists find this stressful and complain
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Daniel Bryan Goodman proslijedio/la je Tweet
Handmade bacteriophage. Now thats what the
#Scientists want to see and work with. The best way to study small creatures. The scientist's puppet...!#biotech#bacteriophage#trending#Listen#likes#BoxingDaypic.twitter.com/kzVg2MpWBzHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
In case anyone else is planning to make this (or just likes it when food is science-d), do yourself a favor and read
@kenjilopezalt: https://www.seriouseats.com/2015/12/food-lab-yorkshire-pudding-popover-best-method-science.html … - just don't expect it to stop people from arguing about pudding.Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Making Yorkshire pudding, and no matter which recipe I read, there is always one comment that says "I'm British, and this recipe is wrong: ...". Rolled my eyes, but then realized I have similar feelings about DNA prep and cloning protocols.
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- a framework for low-N protein engineering with data-efficient deep learning! Had a blast working with brilliant