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The findings of this study are wild: "Almost every trial" pubbed in 5 high-impact med journals over a 6-week period had engaged in outcome switching. The authors sent correction letters to the journals & most were rejected https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-019-3173-2 … #bioethics #researchethics
"All five journals were listed as endorsing CONSORT, but all exhibited extensive breaches... and most rejected correction letters documenting shortcomings... analysis demonstrated extensive misunderstandings among journal editors about correct outcome reporting and CONSORT."
Although we were not looking specifically at outcome switching (and were not tracking in real-time but doing a retrospective analysis), our 2012 study of surgical trials reporting also found considerable failure to meet CONSORT reporting requirementshttps://www.journalacs.org/article/S1072-7515(12)00495-4/abstract …
This is important work and I support journals adopting strict requirements for preregistered outcome reporting, but I wonder how many of these violations were trivial rather than major (changing the conclusions of the study). I know it is usually not possible to know this.
For example, as a reader of these studies I haven’t had the expectation that every prespecified secondary outcome would be stated in the paper.
And I don’t think not following a strict standard that they probably didn’t understand implies all these papers were dishonest. I promise I’m not an NEJM editor alt account lol.
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