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Prikvačeni tweet
Super happy to present recent work with
@DiogoMCamacho & Jim Collins, building a deep learning-based language model for the last remaining biopolymer after DNA, RNA, and proteins:#glycans 1/4https://www.biorxiv.org/content/10.1101/2020.01.10.902114v1 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Did not renew the lease on my flat & already had five(!) visits in the span of one week. Now here's the thing: my lease runs out in 7 MONTHS. And it gets worse: communication via text message, barely 24h heads-up, viewings on the weekend, etc The hell is wrong with this system?
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Daniel Bojar proslijedio/la je Tweet
Check our our foray into
#optogenetics tools to control lipid signaling, a super cool story led by@ReikaTei, just published online at@JCellBiol!#lipidtime#directedevolution https://doi.org/10.1083/jcb.201907013 … Twitter thread/synopsis follows:pic.twitter.com/NmxoQvFuTo
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Shoutout to my former co-workers Krzysztof Krawczyk,
@Scheller123, & Hyojin Kim for their great#synbio work rewiring a whole set of mammalian signaling pathways to control expression of endogenous genes via dCas9 constructs! https://www.nature.com/articles/s41467-020-14397-8 …pic.twitter.com/bntVdkcGrw
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Thanks for giving me the opportunity to present & looking forward to the next presentations! Still a long way to go for glycans & machine learning but I'm sure it will be an exciting journey!https://twitter.com/MITglycobio/status/1222960580388118529 …
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This may be super naive but are there classes of E coli strains? (e.g. are K-12 and K-13 in the K class?) Or are they completely distinct/unorganized and O123 is not more similar to O124 than to, say, EH100?
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Look on my works, ye mighty and despair! Did I just spend hours drawing a snake in Illustrator? Yes. Was it worth it?
, would snake again.pic.twitter.com/ZOjYI7rI0p
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Here's your periodic reminder that this clock was at 7 minutes to midnight during the Cuban missile crisis. At this point, it's no more than a decidedly unscientific instrument of fearmongering, creating numbness by constant terror. Hope spurs to action, fear merely paralyzes.https://twitter.com/WIRED/status/1221221753390800896 …
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Daniel Bojar proslijedio/la je Tweet
Excited to share our latest pre-print
- a framework for low-N protein engineering with data-efficient deep learning! Had a blast working with brilliant @EthanAlley@SurgeBiswas@kesvelt and@geochurch. https://www.biorxiv.org/content/10.1101/2020.01.23.917682v1 … Thread (1/7)Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Daniel Bojar proslijedio/la je Tweet
A short and sweet ;) read. So little we understand about glycobio but a major limiting factor for therapeutic dev. Also gets relatively little academic attention (vs DNA/RNA/proteins), but prob lots of siloed industry knowledge Tools like these democratize their understanding!https://twitter.com/daniel_bojar/status/1216399835739410432 …
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Daniel Bojar proslijedio/la je Tweet
Glycans finally join proteins, DNA, and RNA in getting the language model treatment. Great work by
@daniel_bojar@DiogoMCamacho and Jim Collins. Even better, their model is named SweetTalk. https://www.biorxiv.org/content/10.1101/2020.01.10.902114v1 …pic.twitter.com/BkNF0mTByK
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We are far from done in this space and have really exciting stuff in the works, so stay tuned & read the
@biorxivpreprint! If you think this could be helpful to your work, please reach out; we want this to last and make an impact! 4/4Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
We make thousands and thousands of painstakingly curated glycan sequences available, along with glycan embeddings, trained
#ML models for predicting glycan immunogenicity etc., and of course the code for it all, hopefully fueling further advances! 3/4https://github.com/midas-wyss/sweettalk …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Glycans have it all: dizzying diversity, spectacular sparsity, big branches, and an incredible importance to all of biology. Which is why we used my one true talent - naming things - and created SweetTalk, a first step toward predictive
#glycoengineering. 2/4Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
I'm also STILL battling business books, recommended to me because I read one book on Wall Street in 2018
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Me: adds one cookbook to 260 non-cookbooks in my reading list Recommendation system: hOw AbOuT 50 mOrE cOoKbOoKs Seriously, for what do we even have a whole generation of brilliant machine learning people in ads / recommendation?
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Daniel Bojar proslijedio/la je Tweet
Amazing article about the failure of the amyloid hypothesis of Alzheimer’s Disease, and the groupthink that apparently shut down new ideas. What do my Alzheimer’s-research pals think of this?https://www.statnews.com/2019/06/25/alzheimers-cabal-thwarted-progress-toward-cure/ …
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I was today years old when I found out that healthy human brains have a substantial fraction of cells that lost or gained a whole chromosome. That's why I love biology.https://www.jneurosci.org/content/25/9/2176 …
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