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"What if West Africans had successfully waged biological warfare on would-be European colonizers as the colonizers did to Native Americans" is as valid a question as, say, "what if Rome had developed an industrial revolution"
And both hypotheticals open the door to countless possible worlds, both better and worse than our own. Wakandas and nuclear winters and luxury gay space communism and climate apocalypse.
Anything could have happened, and the fact that what happened did happen is much more down to uncontrollable contingencies than to human endeavor, individual or collective.
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