White Southerners have long lagged behind Northerners in aptitude tests and real world academic achievement. Part of the explanation of the historical gap can be attributed to the high Southern prevalence of hookworm infection, which both lowers IQ and increases absenteeism.
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Everywhere it is currently studied children with hookworm are not just duller, but so drained of energy that they skip classes altogether. One of the ways widespread infection probably affected all Southerners was that it increased adult tolerance for playing hooky.
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