D helps protect Irishmen against rickets and inflammatory diseases, but an expected benefit of the selection was this it provided them with a stronger immunity to schizophrenia than any other North European people. Psychotism is a plus if your body can handle it and they could.
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An indicator of how ruthless selection was for skin color specifically can be seen in the contrast between extremely light Irish skin, moderately light eyes, and their surprisingly dark hair. Black Irish hair color may also have a different cause, mediated by dopamine>ACTH.pic.twitter.com/cLWEyxnCrD
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One manifestation of excessively high glucocorticoids like ACTH is Cushing’s Syndrome, whose symptoms are described by Wikipedia in the following way:pic.twitter.com/UIN0wMltDy
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So are there populations that have gone the other way: where selection against schiz has taken place? You would expect it to happen in urbanized places of the far north and there is some evidence in the clump of low hanging dots in the CEU sample here.pic.twitter.com/UUocVkP85U
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About ¼ of Mormons have Scandinavian surnames, principally Danish and Norwegian, and I think the low hanging cluster of dots on the bottom of CEU represents individuals of majority Scandinavian descent that I know to exist in the dataset.
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Scandinavians are under strong selective pressure to keep schizophrenia low, but their high consumption of fish both reduces the power of that pressure and redirects it away from acting directly upon schiz causing alleles and instead improving omega-3 metabolism instead.
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The population that has probably been under the most ruthless selection again schiz per se are the Finns, who along with their Estonian cousins have the highest PISA scores in Europe. Pfiffer also calculated them as having highest the Edu Attainment PGS of any Europeans.
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Schizophrenia risk increases with every IQ dropped and the same genes that increase schiz risk also impair mental function in normals:https://www.nature.com/articles/s41380-018-0332-x …
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Selection against nuttiness may also help to explain the distinctive Nordic personality: in other words, why they’re so boring. The positives to being sane are obvious; the downsides are that you find yourself living in a country where people stare at a burning log on Christmas.
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I started to suspect was up with you when I saw the awesome barrage of high quality links. It reminded me a lot of me, an autistic dude of Norwegian descent.
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Replying to @crimkadid
What do you think of this? Had to cover the county as apparently my family hasn't moved much hahapic.twitter.com/tURMYq8SF3
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Replying to @MMMalign
HAHA, a half Finn, even better! I wonder if that county is up north? Anyways, you are like a little baby compared to mepic.twitter.com/JYXYj48mvG
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