Corey Duke

@coreygduke

MD-PhD student , neuroscientist , podcaster . Studying the molecular underpinnings of learning and memory.

Birmingham, AL
Vrijeme pridruživanja: travanj 2015.

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  1. Prikvačeni tweet
    13. sij

    The final and best version of our light-induced gene expression manuscript is now available on eNeuro! If you're doing any optically based work in culture, definitely have a look as we detail how to get around an experimental confound:

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  2. proslijedio/la je Tweet
    29. sij

    Updated our manuscript on viral manipulation of interneurons from mice to humans. Now with scATACseq-based enhancer selection and 4 new PV-specific enhancers with exquisite specificity for distinct regions of the brain :

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  3. proslijedio/la je Tweet
    28. sij

    We wrote the review that I wished I'd had when I started my PhD in gene regulation & genomics! Read for our take on the past 40 yrs of enhancer biology, a def of an "enhancer", and how we think modern tech (like CRISPR screens) will enable the next era of understanding the genome

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  4. proslijedio/la je Tweet
    27. sij

    Proud of this first first author paper from my first graduate student, Marco D Carpenter!

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  5. proslijedio/la je Tweet
    22. sij

    Hello everyone. This is the bravest thing I’ve ever done. I’m pleased to endorse both PYTHON and R as candidates for the data science programming language of the United States of America. 🇺🇸

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  6. proslijedio/la je Tweet
    20. sij

    This is a very important paper showing the problems of using AAVs. AAVs ablate neurogenesis in Dentate Gyrus. Great work by the Shtrahman group.

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  7. proslijedio/la je Tweet
    16. sij

    Super excited to share my dissertation work showing the hidden stars of dopamine signaling I am honored to have worked with amazing researchers for this project! A.Covelo, , , , , M.Thomas,

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  8. proslijedio/la je Tweet

    Although neural networks usually require massive datasets to do impressive things, for me the highlight of is the fact that it achieved state-of-the-art using only 30K training examples. Code: Paper:

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  9. proslijedio/la je Tweet
    15. sij

    We worked with to show that distributional RL, a recent development in AI research, can provide insight into previously unexplained elements of dopamine-based learning in the brain. Read the blog: (2/2)

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  10. proslijedio/la je Tweet
    6. sij

    Excited to share our paper out today in ! We used in vivo electrophysiology and calcium imaging with Wire-Free Miniscopes to show that hippocampal synchronization is critical for spatial coding and this breaks down in epileptic mice.

    , , i još njih 7
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  11. proslijedio/la je Tweet

    Our Method of the Year 2019 feature on single-cell multimodal analysis includes Comments from Bing Ren, Sarah Teichmann and Alex Schier . Full text links here: , , .

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  12. proslijedio/la je Tweet
    15. pro 2019.

    Annual lab holiday party selfie stick photo. I’m happy to work with a team of people that are not only fantastic scientists but also just great to be around. Looking forward to 2020!

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  13. proslijedio/la je Tweet
    30. pro 2019.
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  14. proslijedio/la je Tweet
    29. pro 2019.

    My PhD work about imaging accessible chromatin in the cell nucleus by using ATAC-see & super-resolution microscopy will probably be unpublished & remain in my thesis. So while I can't share the data/images since there is still a small chance of publishing, here are what I found:

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  15. proslijedio/la je Tweet
    29. pro 2019.

    1/ A dear friend called me yesterday to talk how he had anal sex without a condom 24 hours earlier. He wanted advice on if he should be worried. He used phrases like: "I did something stupid" "I know I'm being paranoid" "I know I'm a hypochondriac"

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  16. proslijedio/la je Tweet
    20. pro 2019.

    our lab's 2nd preprint is up! calcium imaging 🔬 & engrams 🧠 & opto 💡 OH MY. "Hippocampus and amygdala fear memory engrams re-emerge after contextual fear reinstatement" -- led by the dynamic duo et al.! summary 👇🏽

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  17. proslijedio/la je Tweet
    20. pro 2019.

    A year ago in Nature Biotechnology, Becht et al. argued that UMAP preserved global structure better than t-SNE. Now and me wrote a comment saying that their results were entirely due to the different initialization choices: . Thread. (1/n)

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  18. proslijedio/la je Tweet
    27. stu 2019.

    NIH Director, Francis Collins, M.D., Ph.D, is visiting UAB in 2020! Mark your calendar for Friday, March 6.

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  19. proslijedio/la je Tweet
    24. stu 2019.

    A potential mechanism to explain how endocannabinoids are released from neurons.

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  20. proslijedio/la je Tweet
    8. stu 2019.

    And now in it’s final, peer-reviewer form (and still open access)! Thanks to all of the reviewers for helping improve this paper. Still much to be done with these data- we welcome others to work on them w us (GSE89692)!

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