OK, it looks like I eventually found my own answer: it's because the cells have a "full well" capacity limit in practice...
... it has to be some other reason, like the readout can't handle more bits or something?
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Know what I mean? It's like saying "you have to set it because the low 4 bits are noisy and you might not want them".
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But you'd never do that, you'd just record the low 4 bits too, and then just discard them in software if you didn't like them.
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