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cmuratori's profile
Casey Muratori
Casey Muratori
Casey Muratori
@cmuratori

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Casey Muratori

@cmuratori

I'm worried that the baby thinks people can't change.

Seattle
caseymuratori.com
Joined March 2009

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    1. Hamish Todd  🚂Paris/Brussels/Amsterdam Nov, HMU‏ @hamish_todd 6 Mar 2020
      Replying to @cmuratori @sohakes and

      Patents are the current method of creating a financial incentive to create new drugs. It is very plausible to me that they could be replaced with something else like government bounties, but that couldn't be done overnight.

      1 reply 0 retweets 0 likes
    2. Casey Muratori‏ @cmuratori 6 Mar 2020
      Replying to @hamish_todd @sohakes and

      That is the theory, but the more I've looked at the "create new drugs" industry, the more it looks a lot like patents on the measure may actually cause less new drugs to be created than more.

      2 replies 0 retweets 1 like
    3. ben.js‏ @bentruyman 6 Mar 2020
      Replying to @cmuratori @hamish_todd and

      New prescription drugs cost ~$2.7bn to develop. It seems like the solution would need to include minimizing that number as much as possible, especially in the context of patent reform.

      1 reply 0 retweets 0 likes
    4. Casey Muratori‏ @cmuratori 6 Mar 2020
      Replying to @bentruyman @hamish_todd and

      It is also a massive problem regarding what drugs get developed and produced, because when the cost is $3bln, that eliminates any chance someone will refine a drug that can't really be patented, as well as making it unlikely anyone will produce niche drugs or one-timers.

      1 reply 0 retweets 1 like
    5. Casey Muratori‏ @cmuratori 6 Mar 2020
      Replying to @cmuratori @bentruyman and

      So really the right way to state it would be that patents incentivize companies to develop _certain kinds_ of drugs. They actually _don't_ incentivize companies to make effective drugs of all kinds. It's a very important distinction that gets overlooked.

      1 reply 0 retweets 2 likes
    6. Casey Muratori‏ @cmuratori 6 Mar 2020
      Replying to @cmuratori @bentruyman and

      And extend that a little further and you realize that patents specifically encourage the creation of _exactly those kinds of drugs that make healthcare expensive_! Because drug companies aren't going to invest $3bln into a drug that they can't then pull > $3bln out of us for.

      1 reply 2 retweets 4 likes
    7. Casey Muratori‏ @cmuratori 6 Mar 2020
      Replying to @cmuratori @bentruyman and

      So, circling back around, I'm pretty sure patents are actually horrible for health outcomes, and I'm also pretty sure you can make the case very cleanly using mostly analytical evidence.

      1 reply 0 retweets 0 likes
    8. Casey Muratori‏ @cmuratori 6 Mar 2020
      Replying to @cmuratori @bentruyman and

      There almost certainly exist alternative funding models that have at least slightly fewer drawbacks to patents, which have myriad.

      0 replies 0 retweets 1 like
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      Casey Muratori‏ @cmuratori 6 Mar 2020
      Replying to @Jonathan_Blow @bentruyman and

      There is actually a lot of anecdotal evidence of this - I have heard multiple stories of drug companies not pursuing certain research that was promising simply because they could not find a way to patent the result.

      2:26 PM - 6 Mar 2020
      • 9 Likes
      • Hilário Martins traustitj George Plazomites MaverickRaven Aria Kraft Simon Lundmark Eric Richards Cole Knapp
      2 replies 0 retweets 9 likes
        1. New conversation
        2. Casey Muratori‏ @cmuratori 6 Mar 2020
          Replying to @cmuratori @Jonathan_Blow and

          It would be nice if we had some systemic analysis of it, but yeah, it seems a least the case at first blush that the end result of the patent system is that you only get research that can lead to profitable patents (by definition).

          2 replies 1 retweet 3 likes
        3. Hamish Todd  🚂Paris/Brussels/Amsterdam Nov, HMU‏ @hamish_todd 6 Mar 2020
          Replying to @cmuratori @Jonathan_Blow and

          At least you get some research though! It is absolutely the case that there are many drugs that could exist but aren't being researched, everyone knows this. But I don't see at all what you think getting rid of patents would accomplish(unless it is replaced w/ other incentives)?

          1 reply 0 retweets 0 likes
        4. Show replies
        1. New conversation
        2. Timothy Krell‏ @timothykrell 7 Mar 2020
          Replying to @cmuratori @Jonathan_Blow and

          LDN is a great example of this. Has promising results in a variety of autoimmune conditions but is too cheap and unable to be patented for companies to invest time and research into.https://www.ldnresearchtrust.org/what-is-low-dose-naltrexone-ldn …

          1 reply 0 retweets 0 likes
        3. Hamish Todd  🚂Paris/Brussels/Amsterdam Nov, HMU‏ @hamish_todd 7 Mar 2020
          Replying to @timothykrell @cmuratori and

          Yes, this shows that the patent system is not giving us everything we want. This is true, known to biologists, and should be widely known. I would say it is fairly widely known. But the question is: will getting rid of patents make it so we *do* get more things we want?

          0 replies 0 retweets 1 like
        4. End of conversation

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