A self-driving car without a “murder pedestrian” setting will never move in Manhattan.
Cars work in NYC today because they pose a 
threat to pedestrians 
, so walkers avoid them.
Smart Pedestrians will never yield to Self-driving cars at a Manhattan intersection. – mjesto: DUMBO House
I've long thought this was the death sentence for self-driving cars in cities and thus to Uber's business model. I think both can only work in the suburbs and inter-city.