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It’s not that I don’t want to get excited by remdesivir; it’s just that I’m old enough to remember falling in love with oseltamivir and I can’t go through that again
It’s always the same thing with these meds; they get you with their early efficacy data, and then break your heart when you’re ready to settle down with some solid effectiveness data. I’m not 25 anymore. What I want out of therapeutics is different.
I want a *relationship*, you know? I want *trust.* I mean, what’s up with that shifting primary endpoint and that p=0.059? I want *honesty.* What are your side effects, babe? Are you going to gouge me with your pricing?
We all know what happened between remdesivir and Ebola. And Marburg. There’s baggage, is all I’m saying.
Yeah... I work in clinical trials, have done so for about 15 years. I can count on one hand how many have made it all the way to approval. Wouldn't even have to use all the fingers. And that's not even going in to long-term follow-up.
Spent the '90s coordinating AIDS clinical trials analysis, so....yeah.pic.twitter.com/z4WSbNDoX6
I'd like to know if any antiviral medication for any virus significantly improves someone who is infected. We have antivirals for flu, RSV, varicella and now COVID. You're right, not impressive. But all we got until a vaccine.
There r a whole lotta suckers who just bought Gilead stock. Haven’t they watched Handmaid’s Tale? They should know how this plays out...
Lmfao!
"I feel like we're living through the oseltamivir debacle all over again." https://twitter.com/tnicholsmd/status/1255564743063920640?s=20 …pic.twitter.com/DcDsGwDg1j
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