Multileg trades don’t fill at same price after one block, I wonder if it’s just like hmm idk what’s happening here so let’s just go with making the spread pricier

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ali

@biofeed

Jan 24

Do market making algos in illiquid derivatives have memory?

Lol $reta

Drawdown Entertainment Records

Our Lady of Perpetual Drawdown

Drowndown*

*thoughts one has when living in a perpetual drawndown

In the muck, that’s where the magic happens

In a 0.80 range, 1/25 original after hours move, goal line skirmish if I ever seen one

May have said dance with the one who brung ma one time as well, if you is ya, me could be ma right

I need to stop trying to insert “dance with the one that brung ya” in contract negotiations and interviews, but it just really captures how I feel

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$PLRX discussions this AM

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I wonder why you’d roll a hedge or even a bearish strategy month to month like that, feels like unnecessary theta burn and frictional costs?

Didn’t work again…but I am seeing monster 60p roller back from nov, probably same squad that’s rolling the 22.5P in ISEE…a hedge against their GA position? Beefsquashes

Yvan eht nioj

Saw an elegant timespread in $SRPT last month, nice structure. Rarely, a trade cuts to the heart of the fundamental timeline of a company. Shush and just tell me strikes/expiries and I’ll know everything I need to know

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ali

@biofeed

Jan 17

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Quote Tweet

The Simpsons

@Simpsons_tweets

Jan 17

0:17

"Bart, I have a riddle for you. What's the sound of one hand clapping?"

ali

@biofeed

Jan 17

Young buck next to me just front squat my back squat 😐

Just some thoughts between squat sets #SquatThoughts

Kind of interested in this MTR finding as MRI surrogate for myelin density and that was highly significant for CDI in P1, but I don’t buy the whole brain atrophy stuff

Also why are they touting median stability of patients when exclusion criteria says folks can’t have had a relapse in two years? Is absence of relapse at all predictive of future stability? And stability doesn’t matter given their primary endpoint is improvement lol

Also their primary endpoint of EDSS based CDI feels like a tough hurdle. Why not make it easy on yourself? As blade says, some folks like to ice skate uphill 😂

$ATRA needs 90 patients in EMBOLD with a presumed placebo effect of 5% and presumed treatment effect of 28%, extrapolated from P1

Mt. Sinai Hospital, Chicago. Began as Maimonides Hospital with land purchase in 1909. Actual construction started in 1912. By 1915, the hospital was in foreclosure. The building was bought ca. 1918 and became Mt. Sinai soon after.

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