Youhuang Bai

@biobai

bioinformatics and genomics.

Vrijeme pridruživanja: travanj 2010.

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  1. proslijedio/la je Tweet
    11. stu 2019.

    Characterizing the allele- and haplotype-specific copy number landscape of cancer genomes at single-cell resolution with CHISEL

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  2. proslijedio/la je Tweet
    13. velj 2019.

    Blacklisting variants common in private cohorts but not in public databases optimizes human exome analysis

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  3. proslijedio/la je Tweet
    12. stu 2019.

    Our IPF genome-wide analysis is now available on journal website. In it we identify three new regions of the genome associated with IPF risk in the largest IPF GWAS to date!

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    8. stu 2019.
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    TECHNIQUES: A statistical framework for rare disease diagnosis on Mohammadi et al. in Science

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  6. proslijedio/la je Tweet
    31. lis 2019.

    Very interesting paper in on the effect of NMD in genetic diseases - worth a read for anyone who analyses or thinks about pLoF/PTVs.

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  7. proslijedio/la je Tweet
    31. lis 2019.

    Recently, the Lab identified a new artifact called Barcode Multiplets in data generated with our Single Cell ATAC Solution . Please see our note here .

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    Genome in a Bottle v0.6 Benchmark Structural Variants released in dbVar via

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    Oh yeah, I can’t wait to inspect UMAPs/t-SNEs and ‘surf’ on a trajectory from using this insanity of tool! Amazing!

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  10. proslijedio/la je Tweet
    6. lis 2019.

    Our GTEx companion preprint on characterizing tissue specificity using factor analysis is up. We provide candidate transcription factors that may contribute to tissue specific eQTLs. Led by and with

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  11. proslijedio/la je Tweet
    4. ruj 2019.

    Novel genetic determinants of telomere length from a multi-ethnic analysis of 75,000 whole genome sequences in TOPMed

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  12. proslijedio/la je Tweet

    Here is our journal paper, highlighting those 102 genetic markers for depression:

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  13. proslijedio/la je Tweet
    28. ruj 2019.

    A new framework for calculating a gene stability index from single-cell RNA-seq profiling data. Evaluating stably expressed genes in single cells

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  14. proslijedio/la je Tweet
    25. ruj 2019.

    just updated the Paragraph paper where we now apply graph alignments to SVs identified from all three HiFi datasets in . With

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  15. proslijedio/la je Tweet
    24. ruj 2019.

    Exciting days ahead. The Pangenome Project is going to have tremendous impact on genomics. Setting goals for T2T and comprehensive variant discovery.

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  16. proslijedio/la je Tweet
    22. kol 2019.

    A Nature study shows that aged progenitor cells in the rat central nervous system can be made to behave as young cells by reducing the stiffness of the tissue microenvironment, or by inhibiting the mechanosensitive protein PIEZO1.

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  17. proslijedio/la je Tweet
    23. kol 2019.

    Alveolar Stretch Activation of Endothelial Piezo1 Protects Adherens Junctions and Lung Vascular Barrier

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  18. proslijedio/la je Tweet
    26. kol 2019.

    for | an environmental sensory axis by PIEZO1 is essential for MacroPhage Function | Richard Flavell

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  19. proslijedio/la je Tweet
    2. ruj 2019.

    Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection とか Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels

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  20. 23. ruj 2019.
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