How come many of the same people who complain about elitism in science, insane profit making in scientific publishing, and perverseness of impact factors also proudly celebrate BIG papers in Nature & Co? 

This pride is why the system is so hard to change...
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Lots of people are developing alternatives so I'd say this ground is fairly well trodden. I'm not sure that startup logic is a good idea, because financial pressures are the worst thing about the publication business.
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Your right that having financial pressures are terrible. Though don’t you think the bigger issue is that companies like Elsevier and Springer Nature essentially have a monopoly in the industry? Thus being able to force their terms.
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