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ashishkjha's profile
Ashish K. Jha, MD, MPH
Ashish K. Jha, MD, MPH
Ashish K. Jha, MD, MPH
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@ashishkjha

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Ashish K. Jha, MD, MPHVerified account

@ashishkjha

Physician, researcher, advocate for the notion that an ounce of data is worth a thousand pounds of opinion Views here surely my own Professor, Dean @Brown_SPH

Providence, RI
brown.edu/academics/publ…
Joined May 2009

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    Ashish K. Jha, MD, MPH‏Verified account @ashishkjha 8 Jun 2020

    Ashish K. Jha, MD, MPH Retweeted CNBC

    This from @WHO is getting a lot of attention and creating confusion. I want to quickly share what I understand about this. Bottom line question: Are infected people without symptoms an important cause of spread? My best guess: yes. A threadhttps://twitter.com/CNBC/status/1270057840774983683 …

    Ashish K. Jha, MD, MPH added,

    CNBCVerified account @CNBC
    Coronavirus patients without symptoms aren’t driving the spread of the virus, the WHO says. https://cnb.cx/2XH36hA 
    12:04 PM - 8 Jun 2020
    • 2,273 Retweets
    • 3,672 Likes
    • Fred Barrett Rob Soltysik Meredith Kruse Sarah Alghailani UCHENNA! 🐆 Ricky Tin Tin Sumanth Reddy Stephanie Dalfonzo Donghyun  Rim
    172 replies 2,273 retweets 3,672 likes
      1. New conversation
      2. Ashish K. Jha, MD, MPH‏Verified account @ashishkjha 8 Jun 2020

        First, about 20% of people who are infected likely never develop any symptoms. They are truly asymptomatic. Some variation in estimates on this. Lots of data points but here's a preprint https://www.medrxiv.org/content/10.1101/2020.05.10.20097543v1.full.pdf … 2/5

        23 replies 138 retweets 570 likes
        Show this thread
      3. Ashish K. Jha, MD, MPH‏Verified account @ashishkjha 8 Jun 2020

        So what about the other 80% of people who do have symptoms? Many of them are shedding virus BEFORE they develop symptoms https://www.nature.com/articles/s41591-020-0869-5 … Technically, these folks are PRE-symptomatic, not asymptomatic But they are asymptomatic at the time they are shedding virus 3/5

        10 replies 277 retweets 866 likes
        Show this thread
      4. Ashish K. Jha, MD, MPH‏Verified account @ashishkjha 8 Jun 2020

        Some modeling studies suggest 40-60% of spread is from people when they didn’t have symptoms. Here are a few refs: https://www.acpjournals.org/doi/full/10.7326/M20-3012 … https://www.medrxiv.org/content/10.1101/2020.04.25.20079103v2 … 4/6

        8 replies 184 retweets 614 likes
        Show this thread
      5. Ashish K. Jha, MD, MPH‏Verified account @ashishkjha 8 Jun 2020

        So – it might be @WHO is drawing a distinction between asymptomatic spread and pre-symptomatic spread. And it may be there isn't a lot of asymptomatic spread but plenty of pre-symptomatic spread. Would be helpful to get the full report that they are referencing. 5/6

        18 replies 249 retweets 975 likes
        Show this thread
      6. Ashish K. Jha, MD, MPH‏Verified account @ashishkjha 8 Jun 2020

        Both asymptomatic AND pre-symptomatic spread huge problem for controlling disease Because folks shedding virus while asymptomatic Pre-symptomatic has one advantage: you can use contact tracing to find folks they infected But that doesn’t help prevent presymptomatic spread 6/7

        8 replies 162 retweets 676 likes
        Show this thread
      7. Ashish K. Jha, MD, MPH‏Verified account @ashishkjha 8 Jun 2020

        .@WHO communication here not stellar If folks without symptoms truly "very rarely" spread virus, would be huge. But such a statement by @WHO should be accompanied by data. Asymptomatic spread is Achille's heal of this outbreak Would love to be wrong. Need to see data Fin

        45 replies 196 retweets 1,116 likes
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      8. Ashish K. Jha, MD, MPH‏Verified account @ashishkjha 8 Jun 2020

        More on @WHO comment by @mvankerkhove As I read her follow-on tweets, best guess is she really is differentiating asymptomatic vs pre-symptomatic Two key points: 1. People without symptoms definitely spread disease (so wear a mask) 2. @WHO should be clearer in communication

        46 replies 243 retweets 978 likes
        Show this thread
      9. End of conversation
      1. New conversation
      2. Susan Gaca‏ @SusanGaca1 8 Jun 2020
        Replying to @ashishkjha @WHO

        Thank you! Perhaps WHO can clarify quickly or else risk more people relaxing social distancing and face masks. If wrong could be a real set back to progress.

        1 reply 3 retweets 83 likes
      3. Show replies

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