Hormones in general are mostly synthesized from plants, although they still prescribe Premarin (from pregnant mare urine) for menopause T in particular is easy to synthesize because it's made naturally from cholesterol
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Replying to @arthur_affect @AnaMardoll
the existence of premarin makes me happy because it basically gives you an excuse to have transitioned trans women in period fiction
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Replying to @Nymphomachy @AnaMardoll
Well Premarin didn't exist irl until the 1930s but you could handwave that - people sold "ovarian extract" as a quack remedy for "female problems" all the way back in the 19th century, but it wasn't until 1927 it was discovered the most potent source of animal estrogen is urine
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Replying to @arthur_affect @AnaMardoll
wasn't there a viral tweet a while back that the Galli or something actually did drink some kind of concoction to allegedly transition
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Replying to @Nymphomachy @AnaMardoll
It's *possible* that ancient botanical sources of hormones existed that were potent enough to have a significant effect but my impression is it's unlikely, and the evidence is muddled what with the superstition that characterizes folk medicine
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Like the silphium plant was really really important to the ancient world, to the point that it was harvested to extinction, because of the belief that it was a contraceptive It was sacred to Venus, the modern
symbol may have originated as a silphium fruit1 reply 0 retweets 2 likes -
This *could* be because it was unusually high in phytoestrogens and worked like the Pill But we don't know because it's extinct And we know that the "lesser" substitutes for silphium, like asafoetida, don't work this way (and don't in fact work)
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And we have some reason to doubt because of all the other stuff it was also supposed to do Like it was supposed to have all kinds of other virtues and be generally medicinal
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And in particular because it was sacred to Venus it was supposed to be an aphrodisiac as well Like if a man really wanted to get his fuck on with his wife for a while he'd make sure to put it in both her food and his
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If silphium mimics estradiol it seems... unlikely it would consistently have this effect on the libido of everyone who takes it But who knows
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