Please note that the "hygiene hypothesis" (our immune systems in the modern day are understimulated because our environments are too clean and uniform and that's why we have chronic health problems) is controversial, not settled science, and doesn't mean not to wash your hands
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Even if everything they said was true on its own terms you letting yourself get infected by modern germs wouldn't help It's like saying because car culture has made America less healthy, you should personally sell your car, and start commuting to work by walking down the freeway
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What they actually mean is that your exposure to microorganisms should be more like what our ancestors had "in nature", i.e. you should go outside more and such
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The whole theorized problem is that in nature humans were exposed to a wide variety of different germs, most of which weren't targeted against us, but in urban environments there's a much more concentrated population of germs evolved to infect humans (we're all that's around)
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