Even if everything they said was true on its own terms you letting yourself get infected by modern germs wouldn't help It's like saying because car culture has made America less healthy, you should personally sell your car, and start commuting to work by walking down the freeway
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What they actually mean is that your exposure to microorganisms should be more like what our ancestors had "in nature", i.e. you should go outside more and such
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The whole theorized problem is that in nature humans were exposed to a wide variety of different germs, most of which weren't targeted against us, but in urban environments there's a much more concentrated population of germs evolved to infect humans (we're all that's around)
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And "too clean" in that case would be more like an actual clean room, not every day today life. Our day to day environments aren't that clean.
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Yeah it’s much more about living in sterile environments than about basic hygiene
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People for get that the hygiene hypothesis really only concerns autoimmune disorders and the part of our immune system that evolved to fight *parasites*. Not viruses.
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Yeah the biggest difference between you and your ancestors here is you don't have worms in your gut (and the cells whose job it is to emit toxins and keep the worm population down are the same ones that cause allergic response)
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Since a good chunk of humanity is not so hygienic (even in the developed world), I question that hypothesis.
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"I believe we're not being exposed to enough pathogens to build up our immune systems as we did in paleolithic times, and that's why I shit on the floor."
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And it doesn't even apply to pathogens; it's about multicellular parasites.
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