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apsmunro's profile
Alasdair Munro
Alasdair Munro
Alasdair Munro
Verified account
@apsmunro

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Alasdair MunroVerified account

@apsmunro

Paediatric Registrar | Clinical Research Fellow Paediatric Infectious Diseases @southamptonCRF | Lead Fellow @covboost Trial | Husband and dad | No £COI

United Kingdom
dontforgetthebubbles.com/evidence-summa…
Joined April 2013

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    Alasdair Munro‏Verified account @apsmunro 10 Aug 2020

    A few weeks ago a study from SK got lots of attention for reportedly showed children aged 10 - 19 were just as, or more infectious than adults with #COVID19 But that was not the whole story This study on the very same children shows why https://adc.bmj.com/content/early/2020/08/06/archdischild-2020-319910 … 1/6

    8:55 AM - 10 Aug 2020
    • 229 Retweets
    • 439 Likes
    • yabasic Elizabeth Petro H Theixos, PhD 🏺 Sandra M #ZeroCovid Coaster 🙂 sage hanson Dave Evans Prayerful Pepe Two-faced Tiki
    16 replies 229 retweets 439 likes
      1. New conversation
      2. Alasdair Munro‏Verified account @apsmunro 10 Aug 2020

        They took ALL children with #COVID19 in SK (107 of them, median age 15) and looked at how many secondary cases were associated BUT - they removed cases with *shared exposure", who most likely got infected at the same time as the child What did they find? 2/6

        1 reply 10 retweets 83 likes
        Show this thread
      3. Alasdair Munro‏Verified account @apsmunro 10 Aug 2020

        1 case of onward transmission from 248 household contacts (from a 16y old to their sibling, aged 14y) A secondary attack rate of 0.5% This is compared to a household SAR from adults of 7.6% using the same method of analysis https://ophrp.org/journal/view.php?doi=10.24171/j.phrp.2020.11.2.04 … 3/6pic.twitter.com/jZ4AWWqnKQ

        4 replies 15 retweets 85 likes
        Show this thread
      4. Alasdair Munro‏Verified account @apsmunro 10 Aug 2020

        Important caveats: This extraordinarily low SAR is in the setting of intense infection prevention (child and household members immediately quarantined from each other, caregiver in full PPE!) Some of the excluded cases may have been true secondary cases, but likely few 4/6

        2 replies 11 retweets 83 likes
        Show this thread
      5. Alasdair Munro‏Verified account @apsmunro 10 Aug 2020

        Can children transmit the virus? Of course, and given more exposure I'm certain more household transmission would have occurred Using the same method of assessment, it appears less frequent than from adults in the same circumstances 5/6

        1 reply 14 retweets 99 likes
        Show this thread
      6. Alasdair Munro‏Verified account @apsmunro 10 Aug 2020

        Take away points: - Be careful interpreting studies with lots of confounders - Do not rely on any single study; see the whole literature in context - Children may transmit less readily than adults, but we definitely need more evidence to be sure, or to quantify that fact 6/6

        9 replies 48 retweets 263 likes
        Show this thread
      7. End of conversation
      1. New conversation
      2. Peter Matza‏ @PeterMatza 10 Aug 2020
        Replying to @apsmunro

        pic.twitter.com/8VL5oCUnKW

        1 reply 3 retweets 15 likes
      3. Hans Koppies‏ @HansKoppies 10 Aug 2020
        Replying to @PeterMatza @apsmunro @cricketwyvern

        Thanks for sharing. In which newspaper, and when?

        1 reply 0 retweets 3 likes
      4. Show replies
      1. New conversation
      2. Wes Pegden‏ @WesPegden 10 Aug 2020
        Replying to @apsmunro

        Wes Pegden Retweeted Wes Pegden

        In the meantime, the corresponding author on that GA summer camp study has not responded to multiple emails inquiring for any description of methods or code used in their line-matching procedure.https://twitter.com/WesPegden/status/1290338907721277442 …

        Wes Pegden added,

        Wes Pegden @WesPegden
        Replying to @apsmunro
        One underappreciated aspect of this study is that it is essentially a (very simple) high throughput computational study. In particular, through traditional epidemiological means, they had found only 85 cases: https://www.ajc.com/news/coronavirus-cases-from-north-georgia-youth-camp-outbreak-rising/qN0G9TG38tUX5gurg7Of3O/ … But then through name-matching to a...
        3 replies 8 retweets 63 likes
      3. Alasdair Munro‏Verified account @apsmunro 10 Aug 2020
        Replying to @WesPegden

        I wouldn't hold your breath on that one, but let me know if you get anywhere!

        1 reply 0 retweets 25 likes
      4. Show replies
      1. New conversation
      2. Aybuke‏ @pekikimkibu 10 Aug 2020
        Replying to @apsmunro

        The data is from when schools were closed (says in the original study).

        1 reply 0 retweets 8 likes
      3. Alasdair Munro‏Verified account @apsmunro 10 Aug 2020
        Replying to @pekikimkibu

        Yes, and as this study is specifically about household transmission that would make transmission events even more likely as children would rarely be out of the house (as they say in the study)

        2 replies 0 retweets 23 likes
      4. Show replies

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