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Anthony Khong proslijedio/la je Tweet
Spatio-temporal Proteomic Analysis of Stress Granule disassembly using APEX Reveals Regulation by SUMOylation and links to ALS pathogenesis https://biorxiv.org/cgi/content/short/2020.01.29.830133v1 …
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Anthony Khong proslijedio/la je Tweet
My amazing colleague Jason Lee discovered a novel class of contact sites between ER tubules and membraneless organelles, including p-bodies. He showed one of the potential functions of these contact sites is to mediate membraneless organelles' division.https://science.sciencemag.org/content/367/6477/eaay7108 …
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Anthony Khong proslijedio/la je Tweet
Absence of microexons in brain eIF4G leads to autism phenotypes and cognitive deficits through upregulated synaptic protein expression and perturbed FMRP association - very cool paper!https://www.sciencedirect.com/science/article/pii/S109727652030006X …
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Anthony Khong proslijedio/la je Tweet
Registration is LIVE for RNA GRANULES 2020 Vancouver May 24-26, 2020 in beautiful Vancouver Canada
#RNAGRANULES2020! Confirmed Keynote Speakers: Paul Anderson (Harvard) and Gene Yeo (UCSD). Hope you will join us! Early Bird Rate deadline: March 13, 2020 https://fourwav.es/RNAGRANULES2020Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Anthony Khong proslijedio/la je Tweet
#RNAGRANULES2020 We are happy to also confirm Invited Speakers: Don Cleveland, Takashi Fujita, Roy Parker, Alessia Ruggieri, Christine Vande Velde, Dominique Weil, Benjamin Wolozin. Early Bird Rate deadline: March 13, 2020 Abstract deadline: Apr 17, 2020 https://fourwav.es/RNAGRANULES2020Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Anthony Khong proslijedio/la je Tweet
Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins. - PubMed - NCBI https://www.ncbi.nlm.nih.gov/pubmed/31975687/ …
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Anthony Khong proslijedio/la je Tweet
Luca and Adeline's paper on the role of UBAP2L in stress granule assembly is now online in Current Biology! Go and have a look UBAP2L Forms Distinct Cores that Act in Nucleating Stress Granules Upstream of G3BP1https://www.cell.com/current-biology/fulltext/S0960-9822(19)31615-X#.Xim59w7PHYI.twitter …
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Anthony Khong proslijedio/la je Tweet
bioRxiv: The RNA-binding protein, Rasputin/G3BP, enhances the stability and translation of its target mRNAshttp://dlvr.it/RNVJpt
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Anthony Khong proslijedio/la je Tweet
UBAP2L Forms Distinct Cores that Act in Nucleating Stress Granules Upstream of G3BP1:https://www.cell.com/current-biology/fulltext/S0960-9822(19)31615-X#%20 …
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Anthony Khong proslijedio/la je Tweet
What makes RNase L-dependent bodies (RLBs) different from stress granules upon dsRNA stress? RLBs have a distinct biogenesis pathway, unique RNA and protein composition, and interact differently with P-bodies. New in
@jbiolchem#stressgranules#RNA http://www.jbc.org/content/early/2020/01/02/jbc.RA119.011638 ….pic.twitter.com/WQTHbZEAMY
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Anthony Khong proslijedio/la je Tweet
A new microscope technique shows cells’ fine structure in new detail. The method, developed by Eric Betzig, Harald Hess + colleagues, combines 3D super-resolution fluorescence microscopy and electron microscopy in whole cells. Published today in Science! http://bit.ly/2uWFOIz pic.twitter.com/75emy4ghW0
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Anthony Khong proslijedio/la je Tweet
#SG_paper: "Modulation of RNA Condensation by the DEAD-Box Protein eIF4A" via@CellPressNews from Roy Parker lab.https://www.sciencedirect.com/science/article/pii/S0092867419313935 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Anthony Khong proslijedio/la je Tweet
First pre-print out of our lab! Low or repressed translational states can direct mRNAs to P granules!https://www.biorxiv.org/content/10.1101/2020.01.09.900498v1 …
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Anthony Khong proslijedio/la je Tweet
(1/16) Let’s get ready to rumble! “IRES the Virus” in blue versus “Cappy” in green: a fight to the death on single mRNA (red) in a live-cell cage match. Details from
@amandakoch92 here: https://www.biorxiv.org/content/10.1101/2020.01.09.900829v1 …pic.twitter.com/rjRFxYm4SO
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Congrats Devin Tauber and
@gabtaubhttps://twitter.com/gabtaub/status/1215318668713676800 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Anthony Khong proslijedio/la je Tweet
Our recent work suggests a new role for VCP and a stress-activated ribosome associated quality control (RQC) complex in mRNA release from translation for recruitment to stress granules. https://www.biorxiv.org/content/10.1101/2020.01.05.895342v1 …
@umichrna@tim_stasevich@CUBIOCHEM1@BioFrontiers@UM_Geneticspic.twitter.com/H6f3Ot5zu7
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Anthony Khong proslijedio/la je Tweet
Finally please to share our study on norovirus / stress granule interactions with
@igoodfel, the Parker/Ruggieri labs. Take home message: infection remodels the G3BP1 interactome to evade granules formation! One for@BioCondensates and@anthonykkhong.https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1008250 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
I am excited to share our thoughts on the organization principles of eukaryotic messenger ribonucleoproteins in this fun essay Roy Parker and I wrote this year: https://bit.ly/2QxYPs3 . Looking forward to seeing what the RNA community thinks! Happy New Year!!
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Anthony Khong proslijedio/la je Tweet
We would like to share our new structure with the ribosome/cryoEM comunity. This is the structure of the ribosome bound 5-UTR-IRES of the CrpV.https://www.biorxiv.org/content/10.1101/863761v1 …
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Anthony Khong proslijedio/la je Tweet
Juan's paper is out! exRNA from L.sigmodontis lifestages and detection of parasite RNAs in macrophages in vivo. Foundational (hard) work of relevance to filarial infections. Thanks to all involved
@Jquintanalcala,@Hoy_am,@sujaik@SimonAB,@FranklinChow83https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0007811 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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