Anthony Khong

@anthonykkhong

Postdoc interested in everything RNA related. Representing Canadians in the US of A. Parker lab. Banting fellow.

Vrijeme pridruživanja: listopad 2016.

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  1. proslijedio/la je Tweet
    29. sij

    Spatio-temporal Proteomic Analysis of Stress Granule disassembly using APEX Reveals Regulation by SUMOylation and links to ALS pathogenesis

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  2. proslijedio/la je Tweet
    31. sij

    My amazing colleague Jason Lee discovered a novel class of contact sites between ER tubules and membraneless organelles, including p-bodies. He showed one of the potential functions of these contact sites is to mediate membraneless organelles' division.

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  3. proslijedio/la je Tweet
    29. sij

    Absence of microexons in brain eIF4G leads to autism phenotypes and cognitive deficits through upregulated synaptic protein expression and perturbed FMRP association - very cool paper!

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  4. proslijedio/la je Tweet
    27. sij

    Registration is LIVE for RNA GRANULES 2020 Vancouver May 24-26, 2020 in beautiful Vancouver Canada ! Confirmed Keynote Speakers: Paul Anderson (Harvard) and Gene Yeo (UCSD). Hope you will join us! Early Bird Rate deadline: March 13, 2020

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  5. proslijedio/la je Tweet
    27. sij

    We are happy to also confirm Invited Speakers: Don Cleveland, Takashi Fujita, Roy Parker, Alessia Ruggieri, Christine Vande Velde, Dominique Weil, Benjamin Wolozin. Early Bird Rate deadline: March 13, 2020 Abstract deadline: Apr 17, 2020

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  6. proslijedio/la je Tweet
    25. sij

    Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins. - PubMed - NCBI

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  7. proslijedio/la je Tweet
    23. sij

    Luca and Adeline's paper on the role of UBAP2L in stress granule assembly is now online in Current Biology! Go and have a look UBAP2L Forms Distinct Cores that Act in Nucleating Stress Granules Upstream of G3BP1

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  8. proslijedio/la je Tweet
    22. sij

    bioRxiv: The RNA-binding protein, Rasputin/G3BP, enhances the stability and translation of its target mRNAs

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  9. proslijedio/la je Tweet
    16. sij

    UBAP2L Forms Distinct Cores that Act in Nucleating Stress Granules Upstream of G3BP1:

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  10. proslijedio/la je Tweet
    16. sij

    What makes RNase L-dependent bodies (RLBs) different from stress granules upon dsRNA stress? RLBs have a distinct biogenesis pathway, unique RNA and protein composition, and interact differently with P-bodies. New in .

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  11. proslijedio/la je Tweet
    16. sij

    A new microscope technique shows cells’ fine structure in new detail. The method, developed by Eric Betzig, Harald Hess + colleagues, combines 3D super-resolution fluorescence microscopy and electron microscopy in whole cells. Published today in Science!

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  12. proslijedio/la je Tweet
    14. sij

    : "Modulation of RNA Condensation by the DEAD-Box Protein eIF4A" via from Roy Parker lab.

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  13. proslijedio/la je Tweet
    10. sij

    First pre-print out of our lab! Low or repressed translational states can direct mRNAs to P granules!

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  14. proslijedio/la je Tweet
    10. sij

    (1/16) Let’s get ready to rumble! “IRES the Virus” in blue versus “Cappy” in green: a fight to the death on single mRNA (red) in a live-cell cage match. Details from here:

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  15. 9. sij
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  16. proslijedio/la je Tweet
    7. sij

    Our recent work suggests a new role for VCP and a stress-activated ribosome associated quality control (RQC) complex in mRNA release from translation for recruitment to stress granules.

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  17. proslijedio/la je Tweet
    7. sij

    Finally please to share our study on norovirus / stress granule interactions with , the Parker/Ruggieri labs. Take home message: infection remodels the G3BP1 interactome to evade granules formation! One for and .

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  18. 31. pro 2019.

    I am excited to share our thoughts on the organization principles of eukaryotic messenger ribonucleoproteins in this fun essay Roy Parker and I wrote this year: . Looking forward to seeing what the RNA community thinks! Happy New Year!!

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  19. proslijedio/la je Tweet
    4. pro 2019.

    We would like to share our new structure with the ribosome/cryoEM comunity. This is the structure of the ribosome bound 5-UTR-IRES of the CrpV.

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  20. proslijedio/la je Tweet
    1. pro 2019.

    Juan's paper is out! exRNA from L.sigmodontis lifestages and detection of parasite RNAs in macrophages in vivo. Foundational (hard) work of relevance to filarial infections. Thanks to all involved , , ,

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